Design: Longitudinal training. Objectives: The purpose was to determine the effect of electrical stimulation (ES)-assisted cycling (30 min/day, 3 days/week for 8 weeks) on glucose tolerance and insulin sensitivity in people with spinal cord injury (SCI). Setting: The Steadward Centre, Alberta, Canada. Methods: Seven participants with motor complete SCI (five males and two females aged 30 to 53 years, injured 3-40 years, C5-T10) underwent 2-h oral glucose tolerance tests (OGTT, n = 7) and hyperglycaemic clamp tests (n = 3) before and after 8 weeks of training with ES-assisted cycling. Results: Results indicated that subjects' glucose level were significantly lower at 2 h OGTT following 8 weeks of training (122.4±10 vs 139.9±16, P=0.014). Two-hour hyperglycaemic clamps tests showed improvement in all three people for glucose utilisation and in two of three people for insulin sensitivity. Conclusions: These results suggested that exercise with ES-assisted cycling is beneficial for the prevention and treatment of Type 2 diabetes mellitus in people with SCI. Sponsorship: Supported by Alberta Paraplegic Foundation, Therapeutic Alliance.
Bibliographical noteFunding Information:
We would like to thank the Alberta Paraplegic Foundation for their support with respect to recruitment and financial contributions. We are grateful to James Shorey at Therapeutic Alliance for providing supplies to perform the training protocol for 8 weeks. Lastly, we would like to extend our gratitude to the participants, volunteers who offered their time and effort to see this project to its completion.
All Science Journal Classification (ASJC) codes
- Clinical Neurology