Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth

Eun Sung Kim, Jee Aee Im, Kyoung Chul Kim, Ji Hye Park, Sang Hoon Suh, Eun Seok Kang, So Hun Kim, Yoonsuk Jekal, Chul Won Lee, Yong Jin Yoon, Hyun Chul Lee, Justin Y. Jeon

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130 Citations (Scopus)

Abstract

Objective: The objective of this study was to investigate the association among adiposity, insulin resistance, and inflammatory markers [high-sensitivity C-reactive protein (hs-CRP), interleukin (IL)-6, and tumor necrosis factor (TNF)-α] and adiponectin and to study the effects of exercise training on adiposity, insulin resistance, and inflammatory markers among obese male Korean adolescents. Research Methods and Procedures: Twenty-six obese and 14 lean age-matched male adolescents were studied. We divided the obese subjects into two groups: obese exercise group (N = 14) and obese control group (N = 12). The obese exercise group underwent 6 weeks of jump rope exercise training (40 min/d, 5 d/wk). Adiposity, insulin resistance, lipid profile, hs-CRP, IL-6, TNF-α, and adiponectin were measured before and after the completion of exercise training. Results: The current study demonstrated higher insulin resistance, total cholesterol, LDL-C levels, triglyceride, and inflammatory markers and lower adiponectin and HDL-C in obese Korean male adolescents. Six weeks of increased physical activity improved body composition, insulin sensitivity, and adiponectin levels in obese Korean male adolescents without changes in TNF-α, IL-6, and hs-CRP. Discussion: Obese Korean male adolescents showed reduced adiponectin levels and increased inflammatory cytokines. Six weeks of jump rope exercise improved triglyceride and insulin sensitivity and increased adiponectin levels.

Original languageEnglish
Pages (from-to)3023-3030
Number of pages8
JournalObesity
Volume15
Issue number12
DOIs
Publication statusPublished - 2007 Dec

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

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    Kim, E. S., Im, J. A., Kim, K. C., Park, J. H., Suh, S. H., Kang, E. S., Kim, S. H., Jekal, Y., Lee, C. W., Yoon, Y. J., Lee, H. C., & Jeon, J. Y. (2007). Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth. Obesity, 15(12), 3023-3030. https://doi.org/10.1038/oby.2007.360