Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template

Sang Yup Lee, Elizabeth Royston, James N. Culver, Michael T. Harris

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

Improved depositions of various metal clusters onto a biomolecular template were achieved using a genetically engineered tobacco mosaic virus (TMV). Wild-type TMV was genetically altered to display multiple solid metal binding sites through the insertion of two cysteine residues within the amino-terminus of the virus coat protein. Gold, silver, and palladium clusters synthesized through in situ chemical reductions could be readily deposited onto the genetically modified template via the exposed cysteine-derived thiol groups. Metal cluster coatings on the cysteine-modified template were more densely deposited and stable than similar coatings on the unmodified wild-type template. Combined, these results confirm that the introduction of cysteine residues onto the outer surface of the TMV coat protein enhances the usefulness of this virus as a biotemplate for the deposition of metal clusters.

Original languageEnglish
Pages (from-to)S435-S441
JournalNanotechnology
Volume16
Issue number7
DOIs
Publication statusPublished - 2005 Jul 1

Fingerprint

Tobacco
Viruses
Metals
Cysteine
Capsid Proteins
Proteins
Coatings
Palladium
Binding sites
Silver
Sulfhydryl Compounds
Gold
Binding Sites

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Lee, Sang Yup ; Royston, Elizabeth ; Culver, James N. ; Harris, Michael T. / Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template. In: Nanotechnology. 2005 ; Vol. 16, No. 7. pp. S435-S441.
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Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template. / Lee, Sang Yup; Royston, Elizabeth; Culver, James N.; Harris, Michael T.

In: Nanotechnology, Vol. 16, No. 7, 01.07.2005, p. S435-S441.

Research output: Contribution to journalArticle

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