In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea

Hwa Yum Jong; Ki Kim Chang; Dongeun Yong; Kyungwon Lee; Yunsop Chong; Min Kim Cheol; Mi Kim Jeong; Seonggu Ro; Myung Cho Joong

doi:10.1128/AAC.01562-06

In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea

Hwa Yum Jong, Ki Kim Chang, Dongeun Yong, Kyungwon Lee, Yunsop Chong, Min Kim Cheol, Mi Kim Jeong, Seonggu Ro, Myung Cho Joong

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

The in vitro activities of CG400549, a novel FabI inhibitor, were compared to those of linezolid and commonly used antimicrobials against recent bacterial isolates. CG400549 had an MIC₉₀ of 0.5 μg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin.

Original language	English
Pages (from-to)	2591-2593
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	51
Issue number	7
DOIs	https://doi.org/10.1128/AAC.01562-06
Publication status	Published - 2007 Jul

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.01562-06

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title = "In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea",

abstract = "The in vitro activities of CG400549, a novel FabI inhibitor, were compared to those of linezolid and commonly used antimicrobials against recent bacterial isolates. CG400549 had an MIC90 of 0.5 μg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin.",

author = "Jong, {Hwa Yum} and Chang, {Ki Kim} and Dongeun Yong and Kyungwon Lee and Yunsop Chong and Cheol, {Min Kim} and Jeong, {Mi Kim} and Seonggu Ro and Joong, {Myung Cho}",

year = "2007",

month = jul,

doi = "10.1128/AAC.01562-06",

language = "English",

volume = "51",

pages = "2591--2593",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

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}

In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. / Jong, Hwa Yum; Chang, Ki Kim; Yong, Dongeun ; Lee, Kyungwon; Chong, Yunsop; Cheol, Min Kim; Jeong, Mi Kim; Ro, Seonggu; Joong, Myung Cho.

In: Antimicrobial agents and chemotherapy, Vol. 51, No. 7, 07.2007, p. 2591-2593.

Research output: Contribution to journal › Article › peer-review

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T1 - In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea

AU - Jong, Hwa Yum

AU - Chang, Ki Kim

AU - Yong, Dongeun

AU - Lee, Kyungwon

AU - Chong, Yunsop

AU - Cheol, Min Kim

AU - Jeong, Mi Kim

AU - Ro, Seonggu

AU - Joong, Myung Cho

PY - 2007/7

Y1 - 2007/7

N2 - The in vitro activities of CG400549, a novel FabI inhibitor, were compared to those of linezolid and commonly used antimicrobials against recent bacterial isolates. CG400549 had an MIC90 of 0.5 μg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin.

AB - The in vitro activities of CG400549, a novel FabI inhibitor, were compared to those of linezolid and commonly used antimicrobials against recent bacterial isolates. CG400549 had an MIC90 of 0.5 μg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin.

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SN - 0066-4804

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ER -

In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea

Abstract

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