In vivo bone tissue formation induced by caclium phosphate paste composite with demineralized bone matrix

H. Kim; M. Park; S. Y. Lee; K. Y. Lee; H. M. Kim; S. H. Moon

doi:10.4028/0-87849-422-7.1091

In vivo bone tissue formation induced by caclium phosphate paste composite with demineralized bone matrix

H. Kim, M. Park, S. Y. Lee, K. Y. Lee, H. M. Kim, S. H. Moon

Department of Orthopaedic Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Demineralized bone matrix (DBM)-calcium phosphate cement (CPC) composites were subjected to cellular test of osteogenic potentials and implantation in animal model. The expression of osteogenic marker gene from mouse preosteoblast cell line MC3T3-E1 adhered to the DBM-CPC composite was much higher than plain CPC. In addition, the DBM-CPC composite implanted nude mice revealed osteoinduction between the implanted composite and adjacent tissues, whereas the plain CPC induced osteoconduction.

Original language	English
Pages (from-to)	1091-1094
Number of pages	4
Journal	Key Engineering Materials
Volume	330-332 II
DOIs	https://doi.org/10.4028/0-87849-422-7.1091
Publication status	Published - 2007

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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abstract = "Demineralized bone matrix (DBM)-calcium phosphate cement (CPC) composites were subjected to cellular test of osteogenic potentials and implantation in animal model. The expression of osteogenic marker gene from mouse preosteoblast cell line MC3T3-E1 adhered to the DBM-CPC composite was much higher than plain CPC. In addition, the DBM-CPC composite implanted nude mice revealed osteoinduction between the implanted composite and adjacent tissues, whereas the plain CPC induced osteoconduction.",

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AU - Moon, S. H.

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AB - Demineralized bone matrix (DBM)-calcium phosphate cement (CPC) composites were subjected to cellular test of osteogenic potentials and implantation in animal model. The expression of osteogenic marker gene from mouse preosteoblast cell line MC3T3-E1 adhered to the DBM-CPC composite was much higher than plain CPC. In addition, the DBM-CPC composite implanted nude mice revealed osteoinduction between the implanted composite and adjacent tissues, whereas the plain CPC induced osteoconduction.

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