In vivo selection of carbapenem-resistant Klebsiella pneumoniae by OmpK36 loss during meropenem treatment

Wonkeun Song, Borum Suh, Jun Yong Choi, Seok Hoon Jeong, Eun Hee Jeon, Young Ki Lee, Seong Geun Hong, Kyungwon Lee

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We recovered a carbapenem-resistant Klebsiella pneumoniae isolate H224 under in vivo meropenem selection pressure. Insertional inactivation of a major porin gene, ompK36, by IS5 element might play a role in acquiring carbapenem resistance in this strain harboring plasmid-borne DHA-1 AmpC β-lactamase.

Original languageEnglish
Pages (from-to)447-449
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume65
Issue number4
DOIs
Publication statusPublished - 2009 Dec

Bibliographical note

Funding Information:
This work was supported by the Korea Research Foundation Grant (KRF-2008-E00194).

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'In vivo selection of carbapenem-resistant Klebsiella pneumoniae by OmpK36 loss during meropenem treatment'. Together they form a unique fingerprint.

Cite this