Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: Impact on laboratory diagnosis

Heejung Kim, Thomas V. Riley, Myungsook Kim, Ki Kim Chang, DongEun Yong, Kyungwon Lee, Yunsop Chong, Jong Woo Park

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Of 462 Korean Clostridium difficile isolates, 77.5% were toxin B positive but 21.4% were toxin A negative (A- B+). The binary toxin gene was detected in nine isolates. A higher fluoroquinolone resistance of A- B+ strains may contribute to the increase of these strains. Toxin A detection alone may underdiagnose C. difficile-associated disease.

Original languageEnglish
Pages (from-to)1116-1117
Number of pages2
JournalJournal of Clinical Microbiology
Volume46
Issue number3
DOIs
Publication statusPublished - 2008 Mar 1

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Clostridium difficile
Clinical Laboratory Techniques
Korea
Fluoroquinolones
Genes

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

Kim, Heejung ; Riley, Thomas V. ; Kim, Myungsook ; Chang, Ki Kim ; Yong, DongEun ; Lee, Kyungwon ; Chong, Yunsop ; Park, Jong Woo. / Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea : Impact on laboratory diagnosis. In: Journal of Clinical Microbiology. 2008 ; Vol. 46, No. 3. pp. 1116-1117.
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Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea : Impact on laboratory diagnosis. / Kim, Heejung; Riley, Thomas V.; Kim, Myungsook; Chang, Ki Kim; Yong, DongEun; Lee, Kyungwon; Chong, Yunsop; Park, Jong Woo.

In: Journal of Clinical Microbiology, Vol. 46, No. 3, 01.03.2008, p. 1116-1117.

Research output: Contribution to journalArticle

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