Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: Impact on laboratory diagnosis

Heejung Kim, Thomas V. Riley, Myungsook Kim, Ki Kim Chang, Dongeun Yong, Kyungwon Lee, Yunsop Chong, Jong Woo Park

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Of 462 Korean Clostridium difficile isolates, 77.5% were toxin B positive but 21.4% were toxin A negative (A- B+). The binary toxin gene was detected in nine isolates. A higher fluoroquinolone resistance of A- B+ strains may contribute to the increase of these strains. Toxin A detection alone may underdiagnose C. difficile-associated disease.

Original languageEnglish
Pages (from-to)1116-1117
Number of pages2
JournalJournal of Clinical Microbiology
Issue number3
Publication statusPublished - 2008 Mar 1


All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

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