Increasing Prevalence of Vancomycin-Resistant Enterococcus faecium, Expanded-Spectrum Cephalosporin-Resistant Klebsiella pneumoniae, and Imipenem-Resistant Pseudomonas aeruginosa in Korea: KONSAR Study in 2001

Kyungwon Lee, Sook Jin Jang, Hee Joo Lee, Namhee Ryoo, Myungshin Kim, Seong Geun Hong, Yunsop Chong

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The 5th year KONSAR surveillance in 2001 was based on routine test data at 30 participating hospitals. It was of particular interest to find a trend in the resistances of enterococci to vancomycin, of Enterobacteriaceae to the 3rd generation cephalosporin and fluoroquinolone, and of Pseudomonas aeruginosa and acinetobacters to carbapenem. Resistance rates of Gram-positive cocci were: 70% of Staphylococcus aureus to oxacillin; 88% and 16% of Enterococcus faecium to ampicillin and vancomycin, respectively. Seventy-two percent of pneumococci were nonsusceptible to penicillin. The resistance rates of Enterobacteriaceae were: Escherichia coli, 28% to fluoroquinolone; Klebsiella pneumoniae, 27% to ceftazidime, and 20% to cefoxitin; and Enterobacter cloacae, ≥40% to cefotaxime and ceftazidime. The resistance rates of P. aeruginosa were 21% to ceftazidime, 17% to imipenem, and those of the acinetobacters were ≥61% to ceftazidime, aminoglycosides, fluoroquinolone and cotrimoxazole. Thirty-five percent of non-typhoidal salmonellae were ampicillin resistant, and 66% of Haemophilus influenzae were β-lactamase producers. Notable changes over the 1997-2001 period were: increases in vancomycin-resistant E. faecium, and amikacin- and fluoroquinolone-resistant acinetobacters. With the increasing prevalence of resistant bacteria, nationwide surveillance has become more important for optimal patient management, for the control of nosocomial infection, and for the conservation of the newer antimicrobial agents.

Original languageEnglish
Pages (from-to)8-14
Number of pages7
JournalJournal of Korean medical science
Volume19
Issue number1
DOIs
Publication statusPublished - 2004 Feb

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Enterococcus faecium
Ceftazidime
Imipenem
Fluoroquinolones
Klebsiella pneumoniae
Cephalosporins
Korea
Pseudomonas aeruginosa
Acinetobacter
Enterobacteriaceae
Vancomycin
Ampicillin
Enterobacter cloacae
Cefoxitin
Oxacillin
Gram-Positive Cocci
Carbapenems
Amikacin
Cefotaxime
Sulfamethoxazole Drug Combination Trimethoprim

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{3b093847b47748129a255e078a896061,
title = "Increasing Prevalence of Vancomycin-Resistant Enterococcus faecium, Expanded-Spectrum Cephalosporin-Resistant Klebsiella pneumoniae, and Imipenem-Resistant Pseudomonas aeruginosa in Korea: KONSAR Study in 2001",
abstract = "The 5th year KONSAR surveillance in 2001 was based on routine test data at 30 participating hospitals. It was of particular interest to find a trend in the resistances of enterococci to vancomycin, of Enterobacteriaceae to the 3rd generation cephalosporin and fluoroquinolone, and of Pseudomonas aeruginosa and acinetobacters to carbapenem. Resistance rates of Gram-positive cocci were: 70{\%} of Staphylococcus aureus to oxacillin; 88{\%} and 16{\%} of Enterococcus faecium to ampicillin and vancomycin, respectively. Seventy-two percent of pneumococci were nonsusceptible to penicillin. The resistance rates of Enterobacteriaceae were: Escherichia coli, 28{\%} to fluoroquinolone; Klebsiella pneumoniae, 27{\%} to ceftazidime, and 20{\%} to cefoxitin; and Enterobacter cloacae, ≥40{\%} to cefotaxime and ceftazidime. The resistance rates of P. aeruginosa were 21{\%} to ceftazidime, 17{\%} to imipenem, and those of the acinetobacters were ≥61{\%} to ceftazidime, aminoglycosides, fluoroquinolone and cotrimoxazole. Thirty-five percent of non-typhoidal salmonellae were ampicillin resistant, and 66{\%} of Haemophilus influenzae were β-lactamase producers. Notable changes over the 1997-2001 period were: increases in vancomycin-resistant E. faecium, and amikacin- and fluoroquinolone-resistant acinetobacters. With the increasing prevalence of resistant bacteria, nationwide surveillance has become more important for optimal patient management, for the control of nosocomial infection, and for the conservation of the newer antimicrobial agents.",
author = "Kyungwon Lee and Jang, {Sook Jin} and Lee, {Hee Joo} and Namhee Ryoo and Myungshin Kim and Hong, {Seong Geun} and Yunsop Chong",
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Increasing Prevalence of Vancomycin-Resistant Enterococcus faecium, Expanded-Spectrum Cephalosporin-Resistant Klebsiella pneumoniae, and Imipenem-Resistant Pseudomonas aeruginosa in Korea : KONSAR Study in 2001. / Lee, Kyungwon; Jang, Sook Jin; Lee, Hee Joo; Ryoo, Namhee; Kim, Myungshin; Hong, Seong Geun; Chong, Yunsop.

In: Journal of Korean medical science, Vol. 19, No. 1, 02.2004, p. 8-14.

Research output: Contribution to journalArticle

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T1 - Increasing Prevalence of Vancomycin-Resistant Enterococcus faecium, Expanded-Spectrum Cephalosporin-Resistant Klebsiella pneumoniae, and Imipenem-Resistant Pseudomonas aeruginosa in Korea

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AU - Lee, Kyungwon

AU - Jang, Sook Jin

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AU - Chong, Yunsop

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