Index of Myocardial Performance Using Doppler-Derived Parameters in the Evaluation of Left Ventricular Function in Patients with Essential Hypertension

Seok Min Kang, Jong Won Ha, Se Joong Rim, Namsik Chung

Research output: Contribution to journalArticle

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Abstract

We analyzed Doppler echocardiographic data in 120 subjects with normal sinus rhythm; normals (NL, n=60, ages 54.1±15.1) and essential hypertensive patients (HT, n=60, ages 57.3± 10.2). The IMP was calculated as follows: IMP=(ICT+IRT)/ET, ICT; isovolumic contraction time, IRT; isovolumic relaxation time, ET; ejection time. There were no significant differences in ejection fraction (EF), stroke volume index (SVI), cardiac index (CI), ET and ICT between NL and HT. There were, however, significant differences in deceleration time (DT), E/A ratio, IRT and the IMP between the two groups (199.5±45.6 msec vs 222.3±54.3 msec, p<0.01; 1.4±0.7 vs 0.9±0.2, p<0.01; 113.6±30.2 msec vs 134.2±29.6 msec, p<0.01; 0.6±0.1 vs 0.8±0.3, p<0.05). In HT, there were no differences in EF, SVI, CI, E/A ratio and DT between the NYHA I (Gp I, n=36) and II (Gp II, n=24) groups. However, ET of Gp II was significantly shorter than that of Gp I (259.4±43.5 msec vs 297.8±33.6 msec, p<0.01). ICT, IRT and the IMP were significantly increased in Gp II, compared to those of Gp I (64.4±23.9 msec vs 89.4±46.2 msec, p<0.05; 120.3±21.0 msec vs 155.2±28.5 msec, p<0.001; 0.6±0.2 vs 1.0±0.4, p< 0.001). There were no differences in heart rate and mean blood pressure between Gp I and Gp II (70.9±11.4/min vs 66.3±11.4/min, p>0.05; 138.4±21.2 mmHg vs 131.3±19.9 mmHg, p>0.05). These data suggest that the IMP may be a useful parameter and an early indicator of left ventricular dysfunction in essential hypertensive patients with normal systolic function.

Original languageEnglish
Pages (from-to)446-452
Number of pages7
JournalYonsei medical journal
Volume39
Issue number5
DOIs
Publication statusPublished - 1998 Jan 1

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Inosine Monophosphate
Left Ventricular Function
Deceleration
Left Ventricular Dysfunction
Stroke Volume
Essential Hypertension

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{3f21ddb56bfe4f27a0a717656df68391,
title = "Index of Myocardial Performance Using Doppler-Derived Parameters in the Evaluation of Left Ventricular Function in Patients with Essential Hypertension",
abstract = "We analyzed Doppler echocardiographic data in 120 subjects with normal sinus rhythm; normals (NL, n=60, ages 54.1±15.1) and essential hypertensive patients (HT, n=60, ages 57.3± 10.2). The IMP was calculated as follows: IMP=(ICT+IRT)/ET, ICT; isovolumic contraction time, IRT; isovolumic relaxation time, ET; ejection time. There were no significant differences in ejection fraction (EF), stroke volume index (SVI), cardiac index (CI), ET and ICT between NL and HT. There were, however, significant differences in deceleration time (DT), E/A ratio, IRT and the IMP between the two groups (199.5±45.6 msec vs 222.3±54.3 msec, p<0.01; 1.4±0.7 vs 0.9±0.2, p<0.01; 113.6±30.2 msec vs 134.2±29.6 msec, p<0.01; 0.6±0.1 vs 0.8±0.3, p<0.05). In HT, there were no differences in EF, SVI, CI, E/A ratio and DT between the NYHA I (Gp I, n=36) and II (Gp II, n=24) groups. However, ET of Gp II was significantly shorter than that of Gp I (259.4±43.5 msec vs 297.8±33.6 msec, p<0.01). ICT, IRT and the IMP were significantly increased in Gp II, compared to those of Gp I (64.4±23.9 msec vs 89.4±46.2 msec, p<0.05; 120.3±21.0 msec vs 155.2±28.5 msec, p<0.001; 0.6±0.2 vs 1.0±0.4, p< 0.001). There were no differences in heart rate and mean blood pressure between Gp I and Gp II (70.9±11.4/min vs 66.3±11.4/min, p>0.05; 138.4±21.2 mmHg vs 131.3±19.9 mmHg, p>0.05). These data suggest that the IMP may be a useful parameter and an early indicator of left ventricular dysfunction in essential hypertensive patients with normal systolic function.",
author = "Kang, {Seok Min} and Ha, {Jong Won} and Rim, {Se Joong} and Namsik Chung",
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Index of Myocardial Performance Using Doppler-Derived Parameters in the Evaluation of Left Ventricular Function in Patients with Essential Hypertension. / Kang, Seok Min; Ha, Jong Won; Rim, Se Joong; Chung, Namsik.

In: Yonsei medical journal, Vol. 39, No. 5, 01.01.1998, p. 446-452.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Index of Myocardial Performance Using Doppler-Derived Parameters in the Evaluation of Left Ventricular Function in Patients with Essential Hypertension

AU - Kang, Seok Min

AU - Ha, Jong Won

AU - Rim, Se Joong

AU - Chung, Namsik

PY - 1998/1/1

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N2 - We analyzed Doppler echocardiographic data in 120 subjects with normal sinus rhythm; normals (NL, n=60, ages 54.1±15.1) and essential hypertensive patients (HT, n=60, ages 57.3± 10.2). The IMP was calculated as follows: IMP=(ICT+IRT)/ET, ICT; isovolumic contraction time, IRT; isovolumic relaxation time, ET; ejection time. There were no significant differences in ejection fraction (EF), stroke volume index (SVI), cardiac index (CI), ET and ICT between NL and HT. There were, however, significant differences in deceleration time (DT), E/A ratio, IRT and the IMP between the two groups (199.5±45.6 msec vs 222.3±54.3 msec, p<0.01; 1.4±0.7 vs 0.9±0.2, p<0.01; 113.6±30.2 msec vs 134.2±29.6 msec, p<0.01; 0.6±0.1 vs 0.8±0.3, p<0.05). In HT, there were no differences in EF, SVI, CI, E/A ratio and DT between the NYHA I (Gp I, n=36) and II (Gp II, n=24) groups. However, ET of Gp II was significantly shorter than that of Gp I (259.4±43.5 msec vs 297.8±33.6 msec, p<0.01). ICT, IRT and the IMP were significantly increased in Gp II, compared to those of Gp I (64.4±23.9 msec vs 89.4±46.2 msec, p<0.05; 120.3±21.0 msec vs 155.2±28.5 msec, p<0.001; 0.6±0.2 vs 1.0±0.4, p< 0.001). There were no differences in heart rate and mean blood pressure between Gp I and Gp II (70.9±11.4/min vs 66.3±11.4/min, p>0.05; 138.4±21.2 mmHg vs 131.3±19.9 mmHg, p>0.05). These data suggest that the IMP may be a useful parameter and an early indicator of left ventricular dysfunction in essential hypertensive patients with normal systolic function.

AB - We analyzed Doppler echocardiographic data in 120 subjects with normal sinus rhythm; normals (NL, n=60, ages 54.1±15.1) and essential hypertensive patients (HT, n=60, ages 57.3± 10.2). The IMP was calculated as follows: IMP=(ICT+IRT)/ET, ICT; isovolumic contraction time, IRT; isovolumic relaxation time, ET; ejection time. There were no significant differences in ejection fraction (EF), stroke volume index (SVI), cardiac index (CI), ET and ICT between NL and HT. There were, however, significant differences in deceleration time (DT), E/A ratio, IRT and the IMP between the two groups (199.5±45.6 msec vs 222.3±54.3 msec, p<0.01; 1.4±0.7 vs 0.9±0.2, p<0.01; 113.6±30.2 msec vs 134.2±29.6 msec, p<0.01; 0.6±0.1 vs 0.8±0.3, p<0.05). In HT, there were no differences in EF, SVI, CI, E/A ratio and DT between the NYHA I (Gp I, n=36) and II (Gp II, n=24) groups. However, ET of Gp II was significantly shorter than that of Gp I (259.4±43.5 msec vs 297.8±33.6 msec, p<0.01). ICT, IRT and the IMP were significantly increased in Gp II, compared to those of Gp I (64.4±23.9 msec vs 89.4±46.2 msec, p<0.05; 120.3±21.0 msec vs 155.2±28.5 msec, p<0.001; 0.6±0.2 vs 1.0±0.4, p< 0.001). There were no differences in heart rate and mean blood pressure between Gp I and Gp II (70.9±11.4/min vs 66.3±11.4/min, p>0.05; 138.4±21.2 mmHg vs 131.3±19.9 mmHg, p>0.05). These data suggest that the IMP may be a useful parameter and an early indicator of left ventricular dysfunction in essential hypertensive patients with normal systolic function.

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