Indirect effects of pneumococcal conjugate vaccines in national immunization programs for children on adult pneumococcal disease

Young Keun Kim, David LaFon, Moon H. Nahm

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have included PCVs in national immunization programs for children, the incidence of invasive pneumococcal disease caused by vaccine type Streptococcus pneumoniae has declined markedly, not only among the vaccinated pediatric population, but also among unvaccinated adults. In this review, we present a concise overview of the indirect effects of mass pediatric PCV immunization on unvaccinated adults.

Original languageEnglish
Pages (from-to)257-266
Number of pages10
JournalInfection and Chemotherapy
Volume48
Issue number4
DOIs
Publication statusPublished - 2016

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Pharmacology (medical)

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