Inefficient membrane targeting, translocation, and proteolytic processing by signal peptidase of a mutant preproparathyroid hormone protein

Medicine and Dentistry

• Protein 100%
• Hormone 100%
• Signal Peptide 100%
• Mutant 100%
• Hypoparathyroidism 50%
• Signal Peptidase 50%
• Proteolytic Processing 50%
• Cells 50%
• In Vitro 25%
• Arginine 25%
• Parathyroid Hormone 25%
• Secretion (Process) 25%
• Cysteine 25%
• Codon 25%
• Pulse Rate 25%
• RNA Translation 25%
• Secretory Pathway 25%
• Point Mutation 25%
• Transient Expression 25%
• Inheritance 25%
• Mutant Protein 25%
• Obstruction 25%
• Signal Recognition Particle 25%
• Membrane Targeting 25%
• Patient 25%
• Assay 25%
• Position 25%
• Family 25%

Biochemistry, Genetics and Molecular Biology

• Mutation 100%
• Mutant 100%
• Protein 100%
• Processing 75%
• Signal Peptidase 50%
• Wild Type 25%
• Membrane 25%
• Cysteine 25%
• Secretion (Process) 25%
• Parathyroid Hormone 25%
• Mutant Protein 25%
• Allele 25%
• Arginine 25%
• Point Mutation 25%
• Secretory Pathway 25%
• Codon 25%
• Signal Peptide 25%
• Transient Expression 25%
• RNA Translation 25%
• Pulse Rate 25%
• Inheritance 25%
• Signal Recognition Particle 25%
• Experiment 25%
• Position 25%