Abstract
The genome of influenza virus has become amenable to genetic analysis as a result of newly developed methods for reconstitution of the ribonucleoprotein (RNP) complex. This allows a dissection of the regulatory signals and promoters required for transcription and replication of the viral genome. The ability to rescue chimeric viruses in vivo after transfection opens up a way to engineer viruses suitable for human immunization and carrying desirable antigenic determinants.
Original language | English |
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Pages (from-to) | 17-24 |
Number of pages | 8 |
Journal | Infectious Agents and Disease |
Volume | 2 |
Issue number | 1 |
Publication status | Published - 1993 |
All Science Journal Classification (ASJC) codes
- Microbiology (medical)