Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells

Qing Mu, Hyun Jung Choi, Li Fei Wang, Xiao Jin Li, Jae Sung Hwang, Byeong Gon Lee, Jia Ye, Bi Yan Zhang, Yin Jin Sun, Nam Hoon Cho, Sang Jun Lee, Young Chul Sim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Extracts and fractions from the aerial parts of herbal materials of Saussurea involucrata Kar et Kir ex Maxim (Compositae) were investigated for their whitening activity against mouse-derived immortalized melanocyte cell line. The extract of wild herbs (FS2) possessed a better inhibition (28.2% growth) against melanin cells than that (46.7%) of cultivated herbs (FS1). The whole extracts and middle-polar partitioning fraction show the inhibitory effects, whereas the water-soluble parts show a poor activity in the same assay.

Original languageEnglish
Pages (from-to)678-682
Number of pages5
JournalPharmaceutical Biology
Volume45
Issue number9
DOIs
Publication statusPublished - 2007 Nov 1

Fingerprint

Saussurea
Asteraceae
Melanocytes
Melanins
Cell Line
Water
Growth

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine

Cite this

Mu, Q., Choi, H. J., Wang, L. F., Li, X. J., Hwang, J. S., Lee, B. G., ... Sim, Y. C. (2007). Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells. Pharmaceutical Biology, 45(9), 678-682. https://doi.org/10.1080/13880200701574950
Mu, Qing ; Choi, Hyun Jung ; Wang, Li Fei ; Li, Xiao Jin ; Hwang, Jae Sung ; Lee, Byeong Gon ; Ye, Jia ; Zhang, Bi Yan ; Sun, Yin Jin ; Cho, Nam Hoon ; Lee, Sang Jun ; Sim, Young Chul. / Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells. In: Pharmaceutical Biology. 2007 ; Vol. 45, No. 9. pp. 678-682.
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Mu, Q, Choi, HJ, Wang, LF, Li, XJ, Hwang, JS, Lee, BG, Ye, J, Zhang, BY, Sun, YJ, Cho, NH, Lee, SJ & Sim, YC 2007, 'Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells', Pharmaceutical Biology, vol. 45, no. 9, pp. 678-682. https://doi.org/10.1080/13880200701574950

Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells. / Mu, Qing; Choi, Hyun Jung; Wang, Li Fei; Li, Xiao Jin; Hwang, Jae Sung; Lee, Byeong Gon; Ye, Jia; Zhang, Bi Yan; Sun, Yin Jin; Cho, Nam Hoon; Lee, Sang Jun; Sim, Young Chul.

In: Pharmaceutical Biology, Vol. 45, No. 9, 01.11.2007, p. 678-682.

Research output: Contribution to journalArticle

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AU - Mu, Qing

AU - Choi, Hyun Jung

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AU - Hwang, Jae Sung

AU - Lee, Byeong Gon

AU - Ye, Jia

AU - Zhang, Bi Yan

AU - Sun, Yin Jin

AU - Cho, Nam Hoon

AU - Lee, Sang Jun

AU - Sim, Young Chul

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