Intensity modulation technique using the complementary boost-fields for ethmoid sinus cancer

Sang Wook Lee, Gwi Eon Kim, Chang-Ok Suh, Sung Sil Chu, Kang Kyoo Lee, Sun Rock Moon

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Purpose: To explore a static intensity-modulated radiation therapy (IMRT) technique of a more homogeneous isodose distribution to an irregular-shaped tumour of the ethmoid sinus, with concomitantly sparing the adjacent critical normal organs including the orbit. Methods and Materials: We conducted a static IMRT technique adding 2 or smaller complementary boost-fields to the underdosed volume in the PTV, which resulted from complete blocking of the orbits in all coplanar or non-coplanar main ports of the standard 3-D CRT. The standard 3-D CRT plans (Plan A) and IMRT plans adding complementary boost fields (Plan B) were established for 10 patients with ethmoid sinus cancer. Two sets of different plans for each patient were compared using isodose distribution, dose statistics, and dose volume histogram (DVH) of the planning target volume (PTV) and also using dose statistics and DVH of the adjacent critical structures. Results: The IMRT plans adding 2 or more complementary boost-fields (Plan B) for each patient demonstrated better coverage and improved dose homogeneity of the PTV compared to the standard 3-D CRT plan (Plan A). Moreover, the radiation doses to adjacent normal tissue organs, such as the orbits, optic nerves, brain stem and optic chiasm were similarly spared in both plans. Conclusion: With concomitantly sparing the surrounding visual pathway structures, our IMRT technique using the complementary boost-fields was quantitatively better than current standard 3-D CRT technique with respect to the dose homogeneity within the PTV. Therefore, we believe that our technique, though still not ideal, is thorough enough to be used routinely in treatment of ethmoid sinus tumour.

Original languageEnglish
Pages (from-to)241-249
Number of pages9
JournalClinical Oncology
Volume14
Issue number3
DOIs
Publication statusPublished - 2002 Jan 1

Fingerprint

Ethmoid Sinus
Radiotherapy
Orbit
Neoplasms
Optic Chiasm
Visual Pathways
Optic Nerve
Brain Stem
Radiation

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Lee, Sang Wook ; Kim, Gwi Eon ; Suh, Chang-Ok ; Chu, Sung Sil ; Lee, Kang Kyoo ; Moon, Sun Rock. / Intensity modulation technique using the complementary boost-fields for ethmoid sinus cancer. In: Clinical Oncology. 2002 ; Vol. 14, No. 3. pp. 241-249.
@article{27badd2a92b34ef59582a046088cbe2f,
title = "Intensity modulation technique using the complementary boost-fields for ethmoid sinus cancer",
abstract = "Purpose: To explore a static intensity-modulated radiation therapy (IMRT) technique of a more homogeneous isodose distribution to an irregular-shaped tumour of the ethmoid sinus, with concomitantly sparing the adjacent critical normal organs including the orbit. Methods and Materials: We conducted a static IMRT technique adding 2 or smaller complementary boost-fields to the underdosed volume in the PTV, which resulted from complete blocking of the orbits in all coplanar or non-coplanar main ports of the standard 3-D CRT. The standard 3-D CRT plans (Plan A) and IMRT plans adding complementary boost fields (Plan B) were established for 10 patients with ethmoid sinus cancer. Two sets of different plans for each patient were compared using isodose distribution, dose statistics, and dose volume histogram (DVH) of the planning target volume (PTV) and also using dose statistics and DVH of the adjacent critical structures. Results: The IMRT plans adding 2 or more complementary boost-fields (Plan B) for each patient demonstrated better coverage and improved dose homogeneity of the PTV compared to the standard 3-D CRT plan (Plan A). Moreover, the radiation doses to adjacent normal tissue organs, such as the orbits, optic nerves, brain stem and optic chiasm were similarly spared in both plans. Conclusion: With concomitantly sparing the surrounding visual pathway structures, our IMRT technique using the complementary boost-fields was quantitatively better than current standard 3-D CRT technique with respect to the dose homogeneity within the PTV. Therefore, we believe that our technique, though still not ideal, is thorough enough to be used routinely in treatment of ethmoid sinus tumour.",
author = "Lee, {Sang Wook} and Kim, {Gwi Eon} and Chang-Ok Suh and Chu, {Sung Sil} and Lee, {Kang Kyoo} and Moon, {Sun Rock}",
year = "2002",
month = "1",
day = "1",
doi = "10.1053/clon.2002.0085",
language = "English",
volume = "14",
pages = "241--249",
journal = "Clinical Oncology",
issn = "0936-6555",
publisher = "W.B. Saunders Ltd",
number = "3",

}

Intensity modulation technique using the complementary boost-fields for ethmoid sinus cancer. / Lee, Sang Wook; Kim, Gwi Eon; Suh, Chang-Ok; Chu, Sung Sil; Lee, Kang Kyoo; Moon, Sun Rock.

In: Clinical Oncology, Vol. 14, No. 3, 01.01.2002, p. 241-249.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Intensity modulation technique using the complementary boost-fields for ethmoid sinus cancer

AU - Lee, Sang Wook

AU - Kim, Gwi Eon

AU - Suh, Chang-Ok

AU - Chu, Sung Sil

AU - Lee, Kang Kyoo

AU - Moon, Sun Rock

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Purpose: To explore a static intensity-modulated radiation therapy (IMRT) technique of a more homogeneous isodose distribution to an irregular-shaped tumour of the ethmoid sinus, with concomitantly sparing the adjacent critical normal organs including the orbit. Methods and Materials: We conducted a static IMRT technique adding 2 or smaller complementary boost-fields to the underdosed volume in the PTV, which resulted from complete blocking of the orbits in all coplanar or non-coplanar main ports of the standard 3-D CRT. The standard 3-D CRT plans (Plan A) and IMRT plans adding complementary boost fields (Plan B) were established for 10 patients with ethmoid sinus cancer. Two sets of different plans for each patient were compared using isodose distribution, dose statistics, and dose volume histogram (DVH) of the planning target volume (PTV) and also using dose statistics and DVH of the adjacent critical structures. Results: The IMRT plans adding 2 or more complementary boost-fields (Plan B) for each patient demonstrated better coverage and improved dose homogeneity of the PTV compared to the standard 3-D CRT plan (Plan A). Moreover, the radiation doses to adjacent normal tissue organs, such as the orbits, optic nerves, brain stem and optic chiasm were similarly spared in both plans. Conclusion: With concomitantly sparing the surrounding visual pathway structures, our IMRT technique using the complementary boost-fields was quantitatively better than current standard 3-D CRT technique with respect to the dose homogeneity within the PTV. Therefore, we believe that our technique, though still not ideal, is thorough enough to be used routinely in treatment of ethmoid sinus tumour.

AB - Purpose: To explore a static intensity-modulated radiation therapy (IMRT) technique of a more homogeneous isodose distribution to an irregular-shaped tumour of the ethmoid sinus, with concomitantly sparing the adjacent critical normal organs including the orbit. Methods and Materials: We conducted a static IMRT technique adding 2 or smaller complementary boost-fields to the underdosed volume in the PTV, which resulted from complete blocking of the orbits in all coplanar or non-coplanar main ports of the standard 3-D CRT. The standard 3-D CRT plans (Plan A) and IMRT plans adding complementary boost fields (Plan B) were established for 10 patients with ethmoid sinus cancer. Two sets of different plans for each patient were compared using isodose distribution, dose statistics, and dose volume histogram (DVH) of the planning target volume (PTV) and also using dose statistics and DVH of the adjacent critical structures. Results: The IMRT plans adding 2 or more complementary boost-fields (Plan B) for each patient demonstrated better coverage and improved dose homogeneity of the PTV compared to the standard 3-D CRT plan (Plan A). Moreover, the radiation doses to adjacent normal tissue organs, such as the orbits, optic nerves, brain stem and optic chiasm were similarly spared in both plans. Conclusion: With concomitantly sparing the surrounding visual pathway structures, our IMRT technique using the complementary boost-fields was quantitatively better than current standard 3-D CRT technique with respect to the dose homogeneity within the PTV. Therefore, we believe that our technique, though still not ideal, is thorough enough to be used routinely in treatment of ethmoid sinus tumour.

UR - http://www.scopus.com/inward/record.url?scp=0036594985&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036594985&partnerID=8YFLogxK

U2 - 10.1053/clon.2002.0085

DO - 10.1053/clon.2002.0085

M3 - Article

VL - 14

SP - 241

EP - 249

JO - Clinical Oncology

JF - Clinical Oncology

SN - 0936-6555

IS - 3

ER -