Interactions of a tetraanionic porphyrin with DNA: From a Z-DNA sensor to a versatile supramolecular device

Alessandro D'Urso, Angela Mammana, Milan Balaz, Andrea E. Holmes, Nina Berova, Rosaria Lauceri, Roberto Purrello

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

The anionic nickel(II) porphyrin NiTPPS is able to selectively sense the spermine induced left-handed Z-form of DNA while it is completely silent in the presence of right-handed B-DNA. Interactions between the DNA and the porphyrin can be easily modulated by pH and temperature. The resulting Z-DNA-porphyrin-spermine complex behaves as a supramolecular reversible information storage system and as a reversible AND logic gate.

Original languageEnglish
Pages (from-to)2046-2047
Number of pages2
JournalJournal of the American Chemical Society
Volume131
Issue number6
DOIs
Publication statusPublished - 2009 Feb 18

Fingerprint

Z-Form DNA
Porphyrins
DNA
Spermine
Equipment and Supplies
Sensors
B-Form DNA
Logic gates
Information Storage and Retrieval
Nickel
Information Systems
Data storage equipment
Temperature

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

D'Urso, Alessandro ; Mammana, Angela ; Balaz, Milan ; Holmes, Andrea E. ; Berova, Nina ; Lauceri, Rosaria ; Purrello, Roberto. / Interactions of a tetraanionic porphyrin with DNA : From a Z-DNA sensor to a versatile supramolecular device. In: Journal of the American Chemical Society. 2009 ; Vol. 131, No. 6. pp. 2046-2047.
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Interactions of a tetraanionic porphyrin with DNA : From a Z-DNA sensor to a versatile supramolecular device. / D'Urso, Alessandro; Mammana, Angela; Balaz, Milan; Holmes, Andrea E.; Berova, Nina; Lauceri, Rosaria; Purrello, Roberto.

In: Journal of the American Chemical Society, Vol. 131, No. 6, 18.02.2009, p. 2046-2047.

Research output: Contribution to journalArticle

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AU - Purrello, Roberto

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