Interactions of a tetraanionic porphyrin with DNA: From a Z-DNA sensor to a versatile supramolecular device

Alessandro D'Urso, Angela Mammana, Milan Balaz, Andrea E. Holmes, Nina Berova, Rosaria Lauceri, Roberto Purrello

Research output: Contribution to journalArticle

99 Citations (Scopus)


The anionic nickel(II) porphyrin NiTPPS is able to selectively sense the spermine induced left-handed Z-form of DNA while it is completely silent in the presence of right-handed B-DNA. Interactions between the DNA and the porphyrin can be easily modulated by pH and temperature. The resulting Z-DNA-porphyrin-spermine complex behaves as a supramolecular reversible information storage system and as a reversible AND logic gate.

Original languageEnglish
Pages (from-to)2046-2047
Number of pages2
JournalJournal of the American Chemical Society
Issue number6
Publication statusPublished - 2009 Feb 18


All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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