Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI: A multicenter study (KROG 13-11)

Eonju Lee, Won Park, Sung Hwan Ahn, Jae Ho Cho, Jin Hee Kim, Kwan Ho Cho, Young Min Choi, Jae Sung Kim, Jin Ho Kim, Hong Seok Jang, Young Seok Kim, Taek Keun Nam

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI). Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with the addition of planning MRI. The volumes obtained with CT only and combined CT and MRI were compared, and the effect of the addition of planning MRI on interobserver variability was assessed. Results: There were large differences in clinical target volume (CTV) delineated by each observer, regardless of the addition of planning MRI (9.44–139.27 cm3 in CT only and 7.77–122.83 cm3 in CT plus MRI) and no significant differences in the mean and standard deviation of CTV. However, there were decreases in mean volume and standard deviation as a result of using the planning MRI. Conclusion: This study showed substantial interobserver variation in target volume delineation for salvage radiotherapy. The combination of planning MRI with CT tended to decrease the target volume and the variation.

Original languageEnglish
Pages (from-to)11-16
Number of pages6
JournalRadiation Oncology Journal
Volume36
Issue number1
DOIs
Publication statusPublished - 2018 Mar

Fingerprint

Observer Variation
Prostatectomy
Multicenter Studies
Prostatic Neoplasms
Radiotherapy
Tomography
Magnetic Resonance Imaging

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Lee, Eonju ; Park, Won ; Ahn, Sung Hwan ; Cho, Jae Ho ; Kim, Jin Hee ; Cho, Kwan Ho ; Choi, Young Min ; Kim, Jae Sung ; Kim, Jin Ho ; Jang, Hong Seok ; Kim, Young Seok ; Nam, Taek Keun. / Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI : A multicenter study (KROG 13-11). In: Radiation Oncology Journal. 2018 ; Vol. 36, No. 1. pp. 11-16.
@article{8395708ccedc4671a38f7dfd99b92ffd,
title = "Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI: A multicenter study (KROG 13-11)",
abstract = "Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI). Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with the addition of planning MRI. The volumes obtained with CT only and combined CT and MRI were compared, and the effect of the addition of planning MRI on interobserver variability was assessed. Results: There were large differences in clinical target volume (CTV) delineated by each observer, regardless of the addition of planning MRI (9.44–139.27 cm3 in CT only and 7.77–122.83 cm3 in CT plus MRI) and no significant differences in the mean and standard deviation of CTV. However, there were decreases in mean volume and standard deviation as a result of using the planning MRI. Conclusion: This study showed substantial interobserver variation in target volume delineation for salvage radiotherapy. The combination of planning MRI with CT tended to decrease the target volume and the variation.",
author = "Eonju Lee and Won Park and Ahn, {Sung Hwan} and Cho, {Jae Ho} and Kim, {Jin Hee} and Cho, {Kwan Ho} and Choi, {Young Min} and Kim, {Jae Sung} and Kim, {Jin Ho} and Jang, {Hong Seok} and Kim, {Young Seok} and Nam, {Taek Keun}",
year = "2018",
month = "3",
doi = "10.3857/roj.2017.00080",
language = "English",
volume = "36",
pages = "11--16",
journal = "Radiation Oncology Journal",
issn = "2234-1900",
publisher = "Korean Society for Therapeutic Radiology and Oncology",
number = "1",

}

Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI : A multicenter study (KROG 13-11). / Lee, Eonju; Park, Won; Ahn, Sung Hwan; Cho, Jae Ho; Kim, Jin Hee; Cho, Kwan Ho; Choi, Young Min; Kim, Jae Sung; Kim, Jin Ho; Jang, Hong Seok; Kim, Young Seok; Nam, Taek Keun.

In: Radiation Oncology Journal, Vol. 36, No. 1, 03.2018, p. 11-16.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI

T2 - A multicenter study (KROG 13-11)

AU - Lee, Eonju

AU - Park, Won

AU - Ahn, Sung Hwan

AU - Cho, Jae Ho

AU - Kim, Jin Hee

AU - Cho, Kwan Ho

AU - Choi, Young Min

AU - Kim, Jae Sung

AU - Kim, Jin Ho

AU - Jang, Hong Seok

AU - Kim, Young Seok

AU - Nam, Taek Keun

PY - 2018/3

Y1 - 2018/3

N2 - Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI). Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with the addition of planning MRI. The volumes obtained with CT only and combined CT and MRI were compared, and the effect of the addition of planning MRI on interobserver variability was assessed. Results: There were large differences in clinical target volume (CTV) delineated by each observer, regardless of the addition of planning MRI (9.44–139.27 cm3 in CT only and 7.77–122.83 cm3 in CT plus MRI) and no significant differences in the mean and standard deviation of CTV. However, there were decreases in mean volume and standard deviation as a result of using the planning MRI. Conclusion: This study showed substantial interobserver variation in target volume delineation for salvage radiotherapy. The combination of planning MRI with CT tended to decrease the target volume and the variation.

AB - Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI). Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with the addition of planning MRI. The volumes obtained with CT only and combined CT and MRI were compared, and the effect of the addition of planning MRI on interobserver variability was assessed. Results: There were large differences in clinical target volume (CTV) delineated by each observer, regardless of the addition of planning MRI (9.44–139.27 cm3 in CT only and 7.77–122.83 cm3 in CT plus MRI) and no significant differences in the mean and standard deviation of CTV. However, there were decreases in mean volume and standard deviation as a result of using the planning MRI. Conclusion: This study showed substantial interobserver variation in target volume delineation for salvage radiotherapy. The combination of planning MRI with CT tended to decrease the target volume and the variation.

UR - http://www.scopus.com/inward/record.url?scp=85044727806&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044727806&partnerID=8YFLogxK

U2 - 10.3857/roj.2017.00080

DO - 10.3857/roj.2017.00080

M3 - Article

AN - SCOPUS:85044727806

VL - 36

SP - 11

EP - 16

JO - Radiation Oncology Journal

JF - Radiation Oncology Journal

SN - 2234-1900

IS - 1

ER -