Interspecies dissemination of the bla gene encoding PER-1 extended-spectrum β-lactamase

Il Kwon Bae, Sook Jin Jang, Juwon Kim, Seok Hoon Jeong, Byungkyu Cho, Kyungwon Lee

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26 Citations (Scopus)

Abstract

PER-1 extended-spectrum β-lactamase-producing Gram-negative bacilli are resistant to oxyimino-cephalosporins. However, the blaPER-1 gene has never been reported in Klebsiella pneumoniae. Here, we studied interspecies dissemination of the blaPER-1 gene by horizontal transfer of Tn1213 among Acinetobacter baumannii, Pseudomonas aeruginosa, and K. pneumoniae. In a K. pneumoniae clinical isolate, the blaPER-1 gene was located on a 150-kbp incompatibility group A/C plasmid.

Original languageEnglish
Pages (from-to)1305-1307
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume55
Issue number3
DOIs
Publication statusPublished - 2011 Mar 1

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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