PER-1 extended-spectrum β-lactamase-producing Gram-negative bacilli are resistant to oxyimino-cephalosporins. However, the blaPER-1 gene has never been reported in Klebsiella pneumoniae. Here, we studied interspecies dissemination of the blaPER-1 gene by horizontal transfer of Tn1213 among Acinetobacter baumannii, Pseudomonas aeruginosa, and K. pneumoniae. In a K. pneumoniae clinical isolate, the blaPER-1 gene was located on a 150-kbp incompatibility group A/C plasmid.
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Infectious Diseases