Intestinal Behçet's disease appearing during treatment with adalimumab in a patient with ankylosing spondylitis

Sook Hee Chung, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Tae Il Kim, Won Ho Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Behçet's disease (BD) is a chronic inflammatory disease affecting multiple organ systems, such as the skin, joints, blood vessels, central nervous system, and gastrointestinal tract. Intestinal BD is characterized by intestinal ulcerations and gastrointestinal symptoms. The medical treatment of intestinal BD includes corticosteroids and immunosupressants. There have been several reports of tumor necrosis factor-α (TNF-α) blockers being successful in treatment of refractory intestinal BD. Here, we report on a patient who was diagnosed with intestinal BD despite treatment with the fully humanized TNF-α blocker (adalimumab) for underlying ankylosing spondylitis. This patient achieved clinical remission and complete mucosal healing through the addition of a steroid and azathioprine to the adalimumab regimen.

Original languageEnglish
Pages (from-to)5389-5392
Number of pages4
JournalWorld Journal of Gastroenterology
Volume19
Issue number32
DOIs
Publication statusPublished - 2013 Aug 28

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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