Intravascular ultrasonic predictors of angiographic restenosis after long coronary stenting

Myeong Ki Hong, Seong Wook Park, Gary S. Mintz, Nae Hee Lee, Cheol Whan Lee, Jae Joong Kim, Seung Jung Park

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The intravascular ultrasound (IVUS) criteria for stent optimization have not been determined in stenting long lesions. We evaluated the predictors of angiographic restenosis and compared it with stent lumen cross-sectional area (CSA) and stent length between short (stent length <20 mm) and long (≥20 mm) coronary stenting. IVUS-guided coronary stenting was successfully performed in 285 consecutive patients with 304 native coronary lesions. Six-month follow-up angiogram was performed in 236 patients (82.8%) with 246 lesions (80.9%). Results were evaluated using conventional (clinical, angiographic, and IVUS) methods. The overall angiographic restenosis rate was 22.8% (56 of 246 lesions) (short stent 17.6% vs long stent 32.2%, p = 0.009). Using multivariate logistic regression analysis, the independent predictors of angiographic restenosis were the IVUS stent lumen CSA (odds ratio 1.51, 95% confidence intervals 1.18 to 1.92, p = 0.001) and stent length (odds ratio 0.95, 95% confidence intervals 0.91 to 1.00, p = 0.039). The angiographic restenosis rate was 54.8% for stent lumen CSA of <5.0 mm2 (short stent 37.5% vs long stent 73.3%, p = 0.049), 27.4% for CSA between 5.0 and 7.0 mm2 (short stent 24.1% vs long stent 31.7%, p = 0.409), 10.5% for CSA between 7.0 and 9.0 mm2 (short stent 10.0% vs long stent 12.5%, p = 0.772), and 11.4% for stent lumen CSA of ≥9.0 mm2 (short stent 10.4% vs long stent 13.3%, p = 0.767) (p = 0.001). Compared with short coronary stenting, long coronary stenting is effective treatment modality to cover long lesions with comparable long-term clinical outcomes in cases of stent lumen CSA of ≥7.0 mm2. Regardless of the stent length, the most important factor determining angiographic restenosis was the IVUS stent lumen CSA in relatively large coronary artery lesions. (C) 2000 by Excerpta Medica, Inc.

Original languageEnglish
Pages (from-to)441-445
Number of pages5
JournalAmerican Journal of Cardiology
Volume85
Issue number4
DOIs
Publication statusPublished - 2000 Feb 15

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Ultrasonics
Stents
Odds Ratio
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Hong, Myeong Ki ; Park, Seong Wook ; Mintz, Gary S. ; Lee, Nae Hee ; Lee, Cheol Whan ; Kim, Jae Joong ; Park, Seung Jung. / Intravascular ultrasonic predictors of angiographic restenosis after long coronary stenting. In: American Journal of Cardiology. 2000 ; Vol. 85, No. 4. pp. 441-445.
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abstract = "The intravascular ultrasound (IVUS) criteria for stent optimization have not been determined in stenting long lesions. We evaluated the predictors of angiographic restenosis and compared it with stent lumen cross-sectional area (CSA) and stent length between short (stent length <20 mm) and long (≥20 mm) coronary stenting. IVUS-guided coronary stenting was successfully performed in 285 consecutive patients with 304 native coronary lesions. Six-month follow-up angiogram was performed in 236 patients (82.8{\%}) with 246 lesions (80.9{\%}). Results were evaluated using conventional (clinical, angiographic, and IVUS) methods. The overall angiographic restenosis rate was 22.8{\%} (56 of 246 lesions) (short stent 17.6{\%} vs long stent 32.2{\%}, p = 0.009). Using multivariate logistic regression analysis, the independent predictors of angiographic restenosis were the IVUS stent lumen CSA (odds ratio 1.51, 95{\%} confidence intervals 1.18 to 1.92, p = 0.001) and stent length (odds ratio 0.95, 95{\%} confidence intervals 0.91 to 1.00, p = 0.039). The angiographic restenosis rate was 54.8{\%} for stent lumen CSA of <5.0 mm2 (short stent 37.5{\%} vs long stent 73.3{\%}, p = 0.049), 27.4{\%} for CSA between 5.0 and 7.0 mm2 (short stent 24.1{\%} vs long stent 31.7{\%}, p = 0.409), 10.5{\%} for CSA between 7.0 and 9.0 mm2 (short stent 10.0{\%} vs long stent 12.5{\%}, p = 0.772), and 11.4{\%} for stent lumen CSA of ≥9.0 mm2 (short stent 10.4{\%} vs long stent 13.3{\%}, p = 0.767) (p = 0.001). Compared with short coronary stenting, long coronary stenting is effective treatment modality to cover long lesions with comparable long-term clinical outcomes in cases of stent lumen CSA of ≥7.0 mm2. Regardless of the stent length, the most important factor determining angiographic restenosis was the IVUS stent lumen CSA in relatively large coronary artery lesions. (C) 2000 by Excerpta Medica, Inc.",
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Intravascular ultrasonic predictors of angiographic restenosis after long coronary stenting. / Hong, Myeong Ki; Park, Seong Wook; Mintz, Gary S.; Lee, Nae Hee; Lee, Cheol Whan; Kim, Jae Joong; Park, Seung Jung.

In: American Journal of Cardiology, Vol. 85, No. 4, 15.02.2000, p. 441-445.

Research output: Contribution to journalArticle

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AU - Hong, Myeong Ki

AU - Park, Seong Wook

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AU - Park, Seung Jung

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N2 - The intravascular ultrasound (IVUS) criteria for stent optimization have not been determined in stenting long lesions. We evaluated the predictors of angiographic restenosis and compared it with stent lumen cross-sectional area (CSA) and stent length between short (stent length <20 mm) and long (≥20 mm) coronary stenting. IVUS-guided coronary stenting was successfully performed in 285 consecutive patients with 304 native coronary lesions. Six-month follow-up angiogram was performed in 236 patients (82.8%) with 246 lesions (80.9%). Results were evaluated using conventional (clinical, angiographic, and IVUS) methods. The overall angiographic restenosis rate was 22.8% (56 of 246 lesions) (short stent 17.6% vs long stent 32.2%, p = 0.009). Using multivariate logistic regression analysis, the independent predictors of angiographic restenosis were the IVUS stent lumen CSA (odds ratio 1.51, 95% confidence intervals 1.18 to 1.92, p = 0.001) and stent length (odds ratio 0.95, 95% confidence intervals 0.91 to 1.00, p = 0.039). The angiographic restenosis rate was 54.8% for stent lumen CSA of <5.0 mm2 (short stent 37.5% vs long stent 73.3%, p = 0.049), 27.4% for CSA between 5.0 and 7.0 mm2 (short stent 24.1% vs long stent 31.7%, p = 0.409), 10.5% for CSA between 7.0 and 9.0 mm2 (short stent 10.0% vs long stent 12.5%, p = 0.772), and 11.4% for stent lumen CSA of ≥9.0 mm2 (short stent 10.4% vs long stent 13.3%, p = 0.767) (p = 0.001). Compared with short coronary stenting, long coronary stenting is effective treatment modality to cover long lesions with comparable long-term clinical outcomes in cases of stent lumen CSA of ≥7.0 mm2. Regardless of the stent length, the most important factor determining angiographic restenosis was the IVUS stent lumen CSA in relatively large coronary artery lesions. (C) 2000 by Excerpta Medica, Inc.

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