Intravascular ultrasound assessment of very late bare-metal stent thrombosis

A case report

Ji Hyun Lee, Kyung Min Kim, Junwon Lee, Sung Gyun Ahn, Youngjin Youn

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Very late stent thrombosis (VLST) is increasingly being regarded as a complication of drug-eluting stents (DES), and delayed endothelization, local hypersensitivity reactions, and late stent malapposition due to excessive positive remodeling have been postulated as mechanisms. Considering that stent endothelialization seems to be completed within 4 weeks following bare-metal stent (BMS) placement and that BMS do not possess antiproliferative coating, the mechanism of VLST may differ between patients with DES and those with BMS. We report a case of VLST 9 years after BMS implantation, in which thrombus from the ruptured neointima was confirmed by intravascular ultrasound. This finding suggests that de novo plaque rupture at the neointimal layer within the stent may be one of the explanations for VLST.

Original languageEnglish
Pages (from-to)1658-1660
Number of pages3
JournalChinese Medical Journal
Volume125
Issue number9
DOIs
Publication statusPublished - 2012 Jul 5

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Stents
Thrombosis
Metals
Drug-Eluting Stents
Neointima
Rupture
Hypersensitivity

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Very late stent thrombosis (VLST) is increasingly being regarded as a complication of drug-eluting stents (DES), and delayed endothelization, local hypersensitivity reactions, and late stent malapposition due to excessive positive remodeling have been postulated as mechanisms. Considering that stent endothelialization seems to be completed within 4 weeks following bare-metal stent (BMS) placement and that BMS do not possess antiproliferative coating, the mechanism of VLST may differ between patients with DES and those with BMS. We report a case of VLST 9 years after BMS implantation, in which thrombus from the ruptured neointima was confirmed by intravascular ultrasound. This finding suggests that de novo plaque rupture at the neointimal layer within the stent may be one of the explanations for VLST.",
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Intravascular ultrasound assessment of very late bare-metal stent thrombosis : A case report. / Lee, Ji Hyun; Kim, Kyung Min; Lee, Junwon; Ahn, Sung Gyun; Youn, Youngjin.

In: Chinese Medical Journal, Vol. 125, No. 9, 05.07.2012, p. 1658-1660.

Research output: Contribution to journalArticle

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