Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging

Young Bin Ji, Jung Min Kim, Young Han Lee, Yuna Choi, Da Hee Kim, yongmin Huh, Seung Jae Oh, Yoonwoo Koh, Jinsuck Suh

Research output: Contribution to journalArticle

Abstract

We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.

Original languageEnglish
Pages (from-to)247-256
Number of pages10
JournalJournal of Infrared, Millimeter, and Terahertz Waves
Volume40
Issue number2
DOIs
Publication statusPublished - 2019 Feb 1

Fingerprint

tongue
Water content
moisture content
cancer
Tissue
Imaging techniques
Tumors
tumors
signal reflection
keratins
Keratin
Refractive index
absorptivity
refractivity
coefficients
Epithelial Cells

All Science Journal Classification (ASJC) codes

  • Radiation
  • Instrumentation
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

Cite this

Ji, Young Bin ; Kim, Jung Min ; Lee, Young Han ; Choi, Yuna ; Kim, Da Hee ; Huh, yongmin ; Oh, Seung Jae ; Koh, Yoonwoo ; Suh, Jinsuck. / Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging. In: Journal of Infrared, Millimeter, and Terahertz Waves. 2019 ; Vol. 40, No. 2. pp. 247-256.
@article{935417253d004e50a0bd1a9712143860,
title = "Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging",
abstract = "We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.",
author = "Ji, {Young Bin} and Kim, {Jung Min} and Lee, {Young Han} and Yuna Choi and Kim, {Da Hee} and yongmin Huh and Oh, {Seung Jae} and Yoonwoo Koh and Jinsuck Suh",
year = "2019",
month = "2",
day = "1",
doi = "10.1007/s10762-018-0562-7",
language = "English",
volume = "40",
pages = "247--256",
journal = "Journal of Infrared, Millimeter, and Terahertz Waves",
issn = "1866-6892",
publisher = "Springer New York",
number = "2",

}

Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging. / Ji, Young Bin; Kim, Jung Min; Lee, Young Han; Choi, Yuna; Kim, Da Hee; Huh, yongmin; Oh, Seung Jae; Koh, Yoonwoo; Suh, Jinsuck.

In: Journal of Infrared, Millimeter, and Terahertz Waves, Vol. 40, No. 2, 01.02.2019, p. 247-256.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging

AU - Ji, Young Bin

AU - Kim, Jung Min

AU - Lee, Young Han

AU - Choi, Yuna

AU - Kim, Da Hee

AU - Huh, yongmin

AU - Oh, Seung Jae

AU - Koh, Yoonwoo

AU - Suh, Jinsuck

PY - 2019/2/1

Y1 - 2019/2/1

N2 - We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.

AB - We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.

UR - http://www.scopus.com/inward/record.url?scp=85059592865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85059592865&partnerID=8YFLogxK

U2 - 10.1007/s10762-018-0562-7

DO - 10.1007/s10762-018-0562-7

M3 - Article

AN - SCOPUS:85059592865

VL - 40

SP - 247

EP - 256

JO - Journal of Infrared, Millimeter, and Terahertz Waves

JF - Journal of Infrared, Millimeter, and Terahertz Waves

SN - 1866-6892

IS - 2

ER -