Investigation of the sensitivity enhancement of nanoparticle based surface plasmon resonance biosensors using rigorous coupled wave analysis

Kyung Min Byun, Donghyun Kim, Sung June Kim

Research output: Contribution to journalConference article

11 Citations (Scopus)

Abstract

It is well known that the use of noble metal nanoparticles can considerably enhance the sensitivity of conventional surface plasmon resonance (SPR) biosensors. In our study, we theoretically investigate this sensitivity enhancement effect using rigorous coupled-wave analysis. It is based on the assumption that the enhancement of localized plasmons can be demonstrated by the coupling phenomenon between the periodic noble metal structures and the incident light with an appropriate polarization. It is shown that the rigorous coupled-wave method can be applied to calculating a SPR structure that includes metallic nanoparticles of rectangular-like geometry, where the presence of nanoparticles induces significant changes in the position of reflectivity minimum. The influence of the nanoparticle period on the sensitivity enhancement is also confirmed. In the calculation, Au nanoparticles deposited on an Au film or adsorbed on a SAM layer are modified to regularly patterned one-dimensional nanowires. When the period is less than 300 nm. the calculated sensitivity enhancement of the nanoparticle-based SPR structure is more than ten-fold compared with that of a conventional SPR biosensors configuration.

Original languageEnglish
Article number09
Pages (from-to)61-70
Number of pages10
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume5703
DOIs
Publication statusPublished - 2005 Aug 16
EventPlasmonics in Biology and Medicine II - San Jose, CA, United States
Duration: 2005 Jan 242005 Jan 25

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Surface Plasmon Resonance
Surface plasmon resonance
Biosensing Techniques
bioinstrumentation
surface plasmon resonance
Biosensors
Nanoparticles
Metal Nanoparticles
nanoparticles
augmentation
sensitivity
Precious metals
Nanowires
noble metals
Plasmons
Metal nanoparticles
Metals
plasmons
Light
Polarization

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

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N2 - It is well known that the use of noble metal nanoparticles can considerably enhance the sensitivity of conventional surface plasmon resonance (SPR) biosensors. In our study, we theoretically investigate this sensitivity enhancement effect using rigorous coupled-wave analysis. It is based on the assumption that the enhancement of localized plasmons can be demonstrated by the coupling phenomenon between the periodic noble metal structures and the incident light with an appropriate polarization. It is shown that the rigorous coupled-wave method can be applied to calculating a SPR structure that includes metallic nanoparticles of rectangular-like geometry, where the presence of nanoparticles induces significant changes in the position of reflectivity minimum. The influence of the nanoparticle period on the sensitivity enhancement is also confirmed. In the calculation, Au nanoparticles deposited on an Au film or adsorbed on a SAM layer are modified to regularly patterned one-dimensional nanowires. When the period is less than 300 nm. the calculated sensitivity enhancement of the nanoparticle-based SPR structure is more than ten-fold compared with that of a conventional SPR biosensors configuration.

AB - It is well known that the use of noble metal nanoparticles can considerably enhance the sensitivity of conventional surface plasmon resonance (SPR) biosensors. In our study, we theoretically investigate this sensitivity enhancement effect using rigorous coupled-wave analysis. It is based on the assumption that the enhancement of localized plasmons can be demonstrated by the coupling phenomenon between the periodic noble metal structures and the incident light with an appropriate polarization. It is shown that the rigorous coupled-wave method can be applied to calculating a SPR structure that includes metallic nanoparticles of rectangular-like geometry, where the presence of nanoparticles induces significant changes in the position of reflectivity minimum. The influence of the nanoparticle period on the sensitivity enhancement is also confirmed. In the calculation, Au nanoparticles deposited on an Au film or adsorbed on a SAM layer are modified to regularly patterned one-dimensional nanowires. When the period is less than 300 nm. the calculated sensitivity enhancement of the nanoparticle-based SPR structure is more than ten-fold compared with that of a conventional SPR biosensors configuration.

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