Digital breast tomosynthesis (DBT) is an emerging imaging modality for improved breast cancer detection and diagnosis [1-5]. Numerous efforts have been made to find quantitative metrics associated with mammographic image quality assessment, such as the exponent β of anatomical noise power spectrum, glandularity, contrast noise ratio, etc. [6-8]. In addition, with the use of Fourier-domain detectability for a task-based assessment of DBT, a stationarity assumption on reconstructed image statistics was often made [9-11], resulting in the use of multiple regions-of-interest (ROIs) from different locations in order to increase sample size. While all these metrics provide some information on mammographic image characteristics and signal detection, the relationship between these metrics and detectability in DBT evaluation has not been fully understood. In this work, we investigated spatial-domain detectability trends and levels as a function of the number of slices Ns at three different ROI locations on the same image slice, where background statistics differ in terms of the aforementioned metrics. Detectabilities for the three ROI locations were calculated using multi-slice channelized Hotelling observers with 2D/3D Laguerre-Gauss channels. Our simulation results show that detectability levels and trends as a function of Ns vary across these three ROI locations. They also show that the exponent β, mean glandularity, and mean attenuation coefficient vary across the three ROI locations but they do not necessarily predict the ranking of detectability levels and trends across these ROI locations.
|Title of host publication||Medical Imaging 2016|
|Subtitle of host publication||Image Perception, Observer Performance, and Technology Assessment|
|Editors||Craig K. Abbey, Matthew A. Kupinski|
|Publication status||Published - 2016|
|Event||Medical Imaging 2016: Image Perception, Observer Performance, and Technology Assessment - San Diego, United States|
Duration: 2016 Mar 2 → 2016 Mar 3
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Other||Medical Imaging 2016: Image Perception, Observer Performance, and Technology Assessment|
|Period||16/3/2 → 16/3/3|
Bibliographical notePublisher Copyright:
© 2016 SPIE.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging