Ionic liquid of a gold nanocluster: A versatile matrix for electrochemical biosensors

Kyuju Kwak, S. Senthil Kumar, Kyunglim Pyo, Dongil Lee

Research output: Contribution to journalArticle

91 Citations (Scopus)

Abstract

Ionic liquids are room-temperature molten salts that are increasingly used in electrochemical devices, such as batteries, fuel cells, and sensors, where their intrinsic ionic conductivity is exploited. Here we demonstrate that combining anionic, redox-active Au25 clusters with imidazolium cations leads to a stable ionic liquid possessing both ionic and electronic conductivity. The Au25 ionic liquid was found to act as a versatile matrix for amperometric enzyme biosensors toward the detection of glucose. Enzyme electrodes prepared by incorporating glucose oxidase in the Au 25 ionic liquid show high electrocatalytic activity and substrate affinity. Au25 clusters in the electrode were found to act as effective redox mediators as well as electronic conductors determining the detection sensitivity. With the unique electrochemical properties and almost unlimited structural tunability, the ionic liquids of quantum-sized gold clusters may serve as versatile matrices for a variety of electrochemical biosensors.

Original languageEnglish
Pages (from-to)671-679
Number of pages9
JournalACS Nano
Volume8
Issue number1
DOIs
Publication statusPublished - 2014 Jan 28

Fingerprint

Ionic Liquids
Nanoclusters
nanoclusters
bioinstrumentation
Ionic liquids
Biosensors
Gold
gold
matrices
liquids
glucose
ion currents
enzymes
Fuel cells
Enzyme electrodes
Glucose Oxidase
Glucose oxidase
electrodes
molten salts
oxidase

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Kwak, Kyuju ; Kumar, S. Senthil ; Pyo, Kyunglim ; Lee, Dongil. / Ionic liquid of a gold nanocluster : A versatile matrix for electrochemical biosensors. In: ACS Nano. 2014 ; Vol. 8, No. 1. pp. 671-679.
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Ionic liquid of a gold nanocluster : A versatile matrix for electrochemical biosensors. / Kwak, Kyuju; Kumar, S. Senthil; Pyo, Kyunglim; Lee, Dongil.

In: ACS Nano, Vol. 8, No. 1, 28.01.2014, p. 671-679.

Research output: Contribution to journalArticle

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