Abstract
Purpose: To evaluate the effectiveness, safety, and complications of uterine artery embolization (UAE) in women with large fibroid tumors. Materials and Methods: From January 2005 to February 2011, 323 patients underwent UAE for symptomatic uterine leiomyomas without adenomyosis and were included in this study. Patients were divided into two groups: those with a large tumor burden (group 1; n = 63), defined as a dominant tumor with a longest axis of at least 10 cm or a uterine volume of at least 700 cm3; and the control group (group 2; n = 260). Tumor infarction and volume reduction were calculated based on magnetic resonance imaging findings. Symptom status was assessed with a visual analog scale. Postprocedure complications and repeat interventions were recorded. The data were analyzed with appropriate statistical tests. Results: No significant differences were seen between the two groups in volume reduction of dominant tumors (46.5% in group 1 vs 52.0% in group 2; P =.082) or percentage volume reduction of the uterus (40.7% in group 1 vs 36.3% in group 2; P =.114). Also, no significant differences were seen between the two groups regarding satisfaction scores at immediate or midterm follow-up (P =.524 and P =.497) or in the presence of procedure-related complications (P =.193). Conclusions: UAE outcomes in large fibroid tumors were comparable to those in smaller tumors, without an increased risk of significant complications. Tumor size may not be a key factor in predicting successful outcomes of UAE.
| Original language | English |
|---|---|
| Pages (from-to) | 772-778 |
| Number of pages | 7 |
| Journal | Journal of Vascular and Interventional Radiology |
| Volume | 24 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2013 Jun 1 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine
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Is uterine artery embolization for patients with large myomas safe and effective? A retrospective comparative study in 323 patients. / Choi, Hye Jeong; Jeon, Gyeong Sik; Kim, ManDeuk; Tae Lee, Jong; Hyun Yoon, Jung.
In: Journal of Vascular and Interventional Radiology, Vol. 24, No. 6, 01.06.2013, p. 772-778.Research output: Contribution to journal › Article
TY - JOUR
T1 - Is uterine artery embolization for patients with large myomas safe and effective? A retrospective comparative study in 323 patients
AU - Choi, Hye Jeong
AU - Jeon, Gyeong Sik
AU - Kim, ManDeuk
AU - Tae Lee, Jong
AU - Hyun Yoon, Jung
PY - 2013/6/1
Y1 - 2013/6/1
N2 - Purpose: To evaluate the effectiveness, safety, and complications of uterine artery embolization (UAE) in women with large fibroid tumors. Materials and Methods: From January 2005 to February 2011, 323 patients underwent UAE for symptomatic uterine leiomyomas without adenomyosis and were included in this study. Patients were divided into two groups: those with a large tumor burden (group 1; n = 63), defined as a dominant tumor with a longest axis of at least 10 cm or a uterine volume of at least 700 cm3; and the control group (group 2; n = 260). Tumor infarction and volume reduction were calculated based on magnetic resonance imaging findings. Symptom status was assessed with a visual analog scale. Postprocedure complications and repeat interventions were recorded. The data were analyzed with appropriate statistical tests. Results: No significant differences were seen between the two groups in volume reduction of dominant tumors (46.5% in group 1 vs 52.0% in group 2; P =.082) or percentage volume reduction of the uterus (40.7% in group 1 vs 36.3% in group 2; P =.114). Also, no significant differences were seen between the two groups regarding satisfaction scores at immediate or midterm follow-up (P =.524 and P =.497) or in the presence of procedure-related complications (P =.193). Conclusions: UAE outcomes in large fibroid tumors were comparable to those in smaller tumors, without an increased risk of significant complications. Tumor size may not be a key factor in predicting successful outcomes of UAE.
AB - Purpose: To evaluate the effectiveness, safety, and complications of uterine artery embolization (UAE) in women with large fibroid tumors. Materials and Methods: From January 2005 to February 2011, 323 patients underwent UAE for symptomatic uterine leiomyomas without adenomyosis and were included in this study. Patients were divided into two groups: those with a large tumor burden (group 1; n = 63), defined as a dominant tumor with a longest axis of at least 10 cm or a uterine volume of at least 700 cm3; and the control group (group 2; n = 260). Tumor infarction and volume reduction were calculated based on magnetic resonance imaging findings. Symptom status was assessed with a visual analog scale. Postprocedure complications and repeat interventions were recorded. The data were analyzed with appropriate statistical tests. Results: No significant differences were seen between the two groups in volume reduction of dominant tumors (46.5% in group 1 vs 52.0% in group 2; P =.082) or percentage volume reduction of the uterus (40.7% in group 1 vs 36.3% in group 2; P =.114). Also, no significant differences were seen between the two groups regarding satisfaction scores at immediate or midterm follow-up (P =.524 and P =.497) or in the presence of procedure-related complications (P =.193). Conclusions: UAE outcomes in large fibroid tumors were comparable to those in smaller tumors, without an increased risk of significant complications. Tumor size may not be a key factor in predicting successful outcomes of UAE.
UR - http://www.scopus.com/inward/record.url?scp=84878114277&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878114277&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2013.02.003
DO - 10.1016/j.jvir.2013.02.003
M3 - Article
VL - 24
SP - 772
EP - 778
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
SN - 1051-0443
IS - 6
ER -