Job characteristics and blood coagulation factors in Korean male workers

Sei Jin Chang, Sang Baek Koh, Bong Suk Cha, Jong Ku Park

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


This study examined the possible relationship between Karasek's job strain model and blood coagulation factors VII and VIII as risk factors for cardiovascular disease in Korean male workers. Based on the postulation of the model, we invited 160 male workers (40 people each subgroup) using a stratified sampling from the base population (n = 1071). In univariate analyses, decision latitude was negatively related to blood coagulation factors VII and VIII. Work demand was positively related to coagulation factor VIII, but not to factor VII. Hierarchical multiple regression analyses showed that job strain was associated with blood coagulation factor VIII after controlling for smoking, blood pressure, total cholesterol, and HDL cholesterol. These results indicate that job characteristics may be related to blood coagulation, and contribute to the development of cardiovascular disease with other classical risk factors.

Original languageEnglish
Pages (from-to)997-1002
Number of pages6
JournalJournal of occupational and environmental medicine
Issue number11
Publication statusPublished - 2002 Nov 1

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health


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