Kasabach-Merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid

Taegyun Kim, MiRyung Roh, Soohyun Cho, Kee Yang Chung

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.

Original languageEnglish
Pages (from-to)426-430
Number of pages5
JournalAnnals of Dermatology
Volume22
Issue number4
DOIs
Publication statusPublished - 2010 Nov 1

Fingerprint

Kasabach-Merritt Syndrome
Prednisolone
Adrenal Cortex Hormones
Pubic Bone
Scrotum
Platelet Count
Abdomen
Dexamethasone
Steroids
Recurrence
Therapeutics
Tufted angioma

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

@article{f3d76998dc9b44acaf4748868a4db605,
title = "Kasabach-Merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid",
abstract = "We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.",
author = "Taegyun Kim and MiRyung Roh and Soohyun Cho and Chung, {Kee Yang}",
year = "2010",
month = "11",
day = "1",
doi = "10.5021/ad.2010.22.4.426",
language = "English",
volume = "22",
pages = "426--430",
journal = "Annals of Dermatology",
issn = "1013-9087",
publisher = "Korean Dermatological Association",
number = "4",

}

Kasabach-Merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid. / Kim, Taegyun; Roh, MiRyung; Cho, Soohyun; Chung, Kee Yang.

In: Annals of Dermatology, Vol. 22, No. 4, 01.11.2010, p. 426-430.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Kasabach-Merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid

AU - Kim, Taegyun

AU - Roh, MiRyung

AU - Cho, Soohyun

AU - Chung, Kee Yang

PY - 2010/11/1

Y1 - 2010/11/1

N2 - We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.

AB - We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.

UR - http://www.scopus.com/inward/record.url?scp=79955591960&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955591960&partnerID=8YFLogxK

U2 - 10.5021/ad.2010.22.4.426

DO - 10.5021/ad.2010.22.4.426

M3 - Article

C2 - 21165213

AN - SCOPUS:79955591960

VL - 22

SP - 426

EP - 430

JO - Annals of Dermatology

JF - Annals of Dermatology

SN - 1013-9087

IS - 4

ER -