Key Divisions in the Early Arabidopsis Embryo Require POL and PLL1 Phosphatases to Establish the Root Stem Cell Organizer and Vascular Axis

Sang Kee Song, Hugo Hofhuis, Myeong Min Lee, Steven E. Clark

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Arabidopsis development proceeds from three stem cell populations located at the shoot, flower, and root meristems. The relationship between the highly related shoot and flower stem cells and the very divergent root stem cells has been unclear. We show that the related phosphatases POL and PLL1 are required for all three stem cell populations. pol pll1 mutant embryos lack key asymmetric divisions that give rise to the root stem cell organizer and the central vascular axis. Instead, these cells divide in a superficially symmetric fashion in pol pll1 embryos, leading to a loss of embryonic and postembryonic root stem cells and vascular specification. We present data that show that POL/PLL1 drive root stem cell specification by promoting expression of the WUS homolog WOX5. We propose that POL and PLL1 are required for the proper divisions of shoot, flower, and root stem cell organizers, WUS/WOX5 gene expression, and stem cell maintenance.

Original languageEnglish
Pages (from-to)98-109
Number of pages12
JournalDevelopmental Cell
Volume15
Issue number1
DOIs
Publication statusPublished - 2008 Jul 8

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Stem cells
Phosphoric Monoester Hydrolases
Arabidopsis
Blood Vessels
Stem Cells
Embryonic Structures
Specifications
Meristem
Gene expression
Population
Maintenance
Gene Expression

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

Cite this

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Key Divisions in the Early Arabidopsis Embryo Require POL and PLL1 Phosphatases to Establish the Root Stem Cell Organizer and Vascular Axis. / Song, Sang Kee; Hofhuis, Hugo; Lee, Myeong Min; Clark, Steven E.

In: Developmental Cell, Vol. 15, No. 1, 08.07.2008, p. 98-109.

Research output: Contribution to journalArticle

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