Abstract
We present polarization-sensitive Fourier ptychographic microscopy (PS-FPM) capable of generating high-resolution birefringence images of optically anisotropic specimens over a large field of view (FoV). FPM produces high-resolution images of transparent samples over a large FoV based on multiple intensity measurements acquired at various illumination angles and ptychographic phase retrieval. We combine this attractive feature of FPM with a single-input-state illumination and polarization-diverse imaging system to achieve the imaging of both complex and birefringence information on transparent objects. Compared to conventional polarization imaging techniques, PS-FPM does not involve any mechanical rotation of the polarizer/analyzer and achieves birefringence imaging with a half-pitch resolution of 0.55 μm over 3.78 mm2 FoV, which corresponds to the space-bandwidth product of 12.5 megapixels. We demonstrate the high-resolution, large-area birefringence imaging capability of PS-FPM by presenting the birefringence images of various anisotropic objects including monosodium urate, Tilia stem, and hemozoin crystals.
Original language | English |
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Pages (from-to) | 158-165 |
Number of pages | 8 |
Journal | ACS Photonics |
Volume | 8 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2021 Jan 20 |
Bibliographical note
Publisher Copyright:© 2021 American Chemical Society.
All Science Journal Classification (ASJC) codes
- Biotechnology
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Electrical and Electronic Engineering