Purpose: To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. Methods: This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopia ranged from 3.25 to 7.00 diopters (D). Uncorrected and corrected visual acuity, manifest refraction, epithelial healing time, postoperative pain, subepithelial corneal haze, and complications were examined. Results: Uncorrected visual acuity of 20/30 or better was achieved in 78.6% of eyes at 1 week and in 96.4% at 6 months after surgery. A mean refraction of within ±0.50 D was measured in 42 eyes (50.0%) and ±1.0 D in 79 eyes (94.0%) at 6 months. The epithelial healing time was 3.68 ± 0.69 days (range, 3-6 days) and postoperative pain scores were 1.49 ± 0.65. The subepithelial corneal haze scores were 0.56 ± 0.34 and 0.16 ± 0.25 at 1 and 6 months, respectively. As for complications, alcohol leakage during surgery occurred in 3 eyes, incomplete epithelial detachment in 3 eyes, contact lens intolerance in 5 eyes and steroid-induced elevated intraocular pressure (>21 mm Hg) in 1 eye. Conclusions: LASEK is an effective and safe procedure for low to moderate myopia. It can be considered an alternate type of refractive surgery for correction of low to moderate myopia.
All Science Journal Classification (ASJC) codes