Layer-by-layer assembly of multilayer films for controlled drug release

Daheui Choi; Jinkee Hong

doi:10.1007/s12272-013-0289-x

Layer-by-layer assembly of multilayer films for controlled drug release

Daheui Choi, Jinkee Hong

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Review article › peer-review

33 Citations (Scopus)

Abstract

Drug efficacy has been improved using various methods that enhance targeting, decrease toxicity, and facilitate timely and sustained drug release. To achieve these properties, various drug loading and release platforms have been developed. Layer-by-layer (LbL) self-assembly is widely used to generate controlled and sustained drug release LbL multilayer films because it allows desired functions and structures to be obtained through a simple procedure. In this review article, we highlight controlled drug release from LbL self-assembling films with diverse release kinetics, particularly with regard to mechanisms of drug release.

Original language	English
Pages (from-to)	79-87
Number of pages	9
Journal	Archives of pharmacal research
Volume	37
Issue number	1
DOIs	https://doi.org/10.1007/s12272-013-0289-x
Publication status	Published - 2014 Jan

Bibliographical note

Funding Information:
Acknowledgments This research was supported by the Chung-Ang University Excellent Student Scholarship in 2013 and National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (NRF-2012M3A9C6050104).

All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery
Organic Chemistry

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author = "Daheui Choi and Jinkee Hong",

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AB - Drug efficacy has been improved using various methods that enhance targeting, decrease toxicity, and facilitate timely and sustained drug release. To achieve these properties, various drug loading and release platforms have been developed. Layer-by-layer (LbL) self-assembly is widely used to generate controlled and sustained drug release LbL multilayer films because it allows desired functions and structures to be obtained through a simple procedure. In this review article, we highlight controlled drug release from LbL self-assembling films with diverse release kinetics, particularly with regard to mechanisms of drug release.

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Layer-by-layer assembly of multilayer films for controlled drug release

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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