Abstract
Background: The objective of this study was to investigate atrial myocardial properties through two-dimensional (2D) myocardial imaging in patients with atrial fibrillation (AF) and its predictive role for recurrence after catheter ablation. Methods and results: Echocardiographic examinations were performed in 40 patients with paroxysmal AF before catheter ablation and 40 age- and gender-matched healthy control subjects. Using a software package, bidimensional acquisitions were analyzed to measure longitudinal strain and strain rate for the left atrium (LA). Systolic strain and strain rate in all eight segments, and its average values, were significantly reduced in AF patients compared to controls. During 9 months of follow-up after catheter ablation for AF, 11 of 40 AF patients had AF recurrence. AF recurrence was associated with gender, LA volume index, and average values of systolic strain and strain rate. By multivariate analysis, only average strain was an independent predictor of AF recurrence (OR = 0.88, 95% CI 0.79-0.98, p = 0.018). Conclusions: Lower systolic strain of LA was strongly associated with recurrence after catheter ablation. Thus, diverse adjunctive ablation strategies should be considered to reduce recurrence in patients with lower systolic strain.
| Original language | English |
|---|---|
| Pages (from-to) | 127-132 |
| Number of pages | 6 |
| Journal | Journal of Interventional Cardiac Electrophysiology |
| Volume | 26 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2009 Nov 1 |
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All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
- Physiology (medical)
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Left atrial strain as predictor of successful outcomes in catheter ablation for atrial fibrillation : A two-dimensional myocardial imaging study. / Hwang, Hye Jin; Choi, Eui Young; Rhee, Sang Jae; Joung, Boyoung; Lee, Byung Ho; Lee, Sang Hee; Kim, Jaedeok; Lee, Moon Hyoung; Jang, Yangsoo; Chung, Namsik; Kim, Sung Soon.
In: Journal of Interventional Cardiac Electrophysiology, Vol. 26, No. 2, 01.11.2009, p. 127-132.Research output: Contribution to journal › Article
TY - JOUR
T1 - Left atrial strain as predictor of successful outcomes in catheter ablation for atrial fibrillation
T2 - A two-dimensional myocardial imaging study
AU - Hwang, Hye Jin
AU - Choi, Eui Young
AU - Rhee, Sang Jae
AU - Joung, Boyoung
AU - Lee, Byung Ho
AU - Lee, Sang Hee
AU - Kim, Jaedeok
AU - Lee, Moon Hyoung
AU - Jang, Yangsoo
AU - Chung, Namsik
AU - Kim, Sung Soon
PY - 2009/11/1
Y1 - 2009/11/1
N2 - Background: The objective of this study was to investigate atrial myocardial properties through two-dimensional (2D) myocardial imaging in patients with atrial fibrillation (AF) and its predictive role for recurrence after catheter ablation. Methods and results: Echocardiographic examinations were performed in 40 patients with paroxysmal AF before catheter ablation and 40 age- and gender-matched healthy control subjects. Using a software package, bidimensional acquisitions were analyzed to measure longitudinal strain and strain rate for the left atrium (LA). Systolic strain and strain rate in all eight segments, and its average values, were significantly reduced in AF patients compared to controls. During 9 months of follow-up after catheter ablation for AF, 11 of 40 AF patients had AF recurrence. AF recurrence was associated with gender, LA volume index, and average values of systolic strain and strain rate. By multivariate analysis, only average strain was an independent predictor of AF recurrence (OR = 0.88, 95% CI 0.79-0.98, p = 0.018). Conclusions: Lower systolic strain of LA was strongly associated with recurrence after catheter ablation. Thus, diverse adjunctive ablation strategies should be considered to reduce recurrence in patients with lower systolic strain.
AB - Background: The objective of this study was to investigate atrial myocardial properties through two-dimensional (2D) myocardial imaging in patients with atrial fibrillation (AF) and its predictive role for recurrence after catheter ablation. Methods and results: Echocardiographic examinations were performed in 40 patients with paroxysmal AF before catheter ablation and 40 age- and gender-matched healthy control subjects. Using a software package, bidimensional acquisitions were analyzed to measure longitudinal strain and strain rate for the left atrium (LA). Systolic strain and strain rate in all eight segments, and its average values, were significantly reduced in AF patients compared to controls. During 9 months of follow-up after catheter ablation for AF, 11 of 40 AF patients had AF recurrence. AF recurrence was associated with gender, LA volume index, and average values of systolic strain and strain rate. By multivariate analysis, only average strain was an independent predictor of AF recurrence (OR = 0.88, 95% CI 0.79-0.98, p = 0.018). Conclusions: Lower systolic strain of LA was strongly associated with recurrence after catheter ablation. Thus, diverse adjunctive ablation strategies should be considered to reduce recurrence in patients with lower systolic strain.
UR - http://www.scopus.com/inward/record.url?scp=75549088947&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=75549088947&partnerID=8YFLogxK
U2 - 10.1007/s10840-009-9410-y
DO - 10.1007/s10840-009-9410-y
M3 - Article
C2 - 19529886
AN - SCOPUS:75549088947
VL - 26
SP - 127
EP - 132
JO - Journal of Interventional Cardiac Electrophysiology
JF - Journal of Interventional Cardiac Electrophysiology
SN - 1383-875X
IS - 2
ER -