Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia

Hyemoon Chung, Boyoung Joung, Kyung Yul Lee, Jae Sun Uhm, huinam pak, Moon Hyoung Lee, Jong Youn Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF. Methods We investigated the risk factors for predicting the stroke recurrence in NSAT patients. In total, 252 patients (114 women, mean 70 ± 11 years) with acute ischemic stroke and documented NSAT in 24-hour Holter monitoring were enrolled and followed. All patients underwent echo-Doppler evaluations. Results During a mean follow-up period of 35 ± 31 months, the stroke recurrence rate was 11.1% (28 of 252). The patients with recurrence (n = 28) had higher left atrium volume index (LAVI, P <.001) and higher E/e' (P =.028) compared with those without recurrence (n = 224). On the Kaplan-Meier survival analysis, stroke recurrence rate was significantly higher in patients with enlarged LA (LAVI >28 mm3/m2; P <.001 by the log-rank test), and it remained significant in multivariate analysis (hazard ratio, 1.154; 95% confidence interval [CI], 1.099-1.212, P <.001). Conclusions In patients with acute ischemic stroke and NSAT, enlarged LA predicts an increased risk of stroke recurrence. This study supports the necessity of prolonged rhythm monitoring in stroke patients with NSAT and enlarged LA to detect undiagnosed AF and consequently considering anticoagulation therapy.

Original languageEnglish
Pages (from-to)2408-2415
Number of pages8
JournalJournal of Stroke and Cerebrovascular Diseases
Volume24
Issue number10
DOIs
Publication statusPublished - 2015 Oct 1

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Tachycardia
Stroke
Recurrence
Heart Atria
Atrial Fibrillation
Ambulatory Electrocardiography
Multivariate Analysis
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Chung, Hyemoon ; Joung, Boyoung ; Lee, Kyung Yul ; Uhm, Jae Sun ; pak, huinam ; Lee, Moon Hyoung ; Kim, Jong Youn. / Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia. In: Journal of Stroke and Cerebrovascular Diseases. 2015 ; Vol. 24, No. 10. pp. 2408-2415.
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abstract = "Background Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF. Methods We investigated the risk factors for predicting the stroke recurrence in NSAT patients. In total, 252 patients (114 women, mean 70 ± 11 years) with acute ischemic stroke and documented NSAT in 24-hour Holter monitoring were enrolled and followed. All patients underwent echo-Doppler evaluations. Results During a mean follow-up period of 35 ± 31 months, the stroke recurrence rate was 11.1{\%} (28 of 252). The patients with recurrence (n = 28) had higher left atrium volume index (LAVI, P <.001) and higher E/e' (P =.028) compared with those without recurrence (n = 224). On the Kaplan-Meier survival analysis, stroke recurrence rate was significantly higher in patients with enlarged LA (LAVI >28 mm3/m2; P <.001 by the log-rank test), and it remained significant in multivariate analysis (hazard ratio, 1.154; 95{\%} confidence interval [CI], 1.099-1.212, P <.001). Conclusions In patients with acute ischemic stroke and NSAT, enlarged LA predicts an increased risk of stroke recurrence. This study supports the necessity of prolonged rhythm monitoring in stroke patients with NSAT and enlarged LA to detect undiagnosed AF and consequently considering anticoagulation therapy.",
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Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia. / Chung, Hyemoon; Joung, Boyoung; Lee, Kyung Yul; Uhm, Jae Sun; pak, huinam; Lee, Moon Hyoung; Kim, Jong Youn.

In: Journal of Stroke and Cerebrovascular Diseases, Vol. 24, No. 10, 01.10.2015, p. 2408-2415.

Research output: Contribution to journalArticle

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T1 - Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia

AU - Chung, Hyemoon

AU - Joung, Boyoung

AU - Lee, Kyung Yul

AU - Uhm, Jae Sun

AU - pak, huinam

AU - Lee, Moon Hyoung

AU - Kim, Jong Youn

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N2 - Background Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF. Methods We investigated the risk factors for predicting the stroke recurrence in NSAT patients. In total, 252 patients (114 women, mean 70 ± 11 years) with acute ischemic stroke and documented NSAT in 24-hour Holter monitoring were enrolled and followed. All patients underwent echo-Doppler evaluations. Results During a mean follow-up period of 35 ± 31 months, the stroke recurrence rate was 11.1% (28 of 252). The patients with recurrence (n = 28) had higher left atrium volume index (LAVI, P <.001) and higher E/e' (P =.028) compared with those without recurrence (n = 224). On the Kaplan-Meier survival analysis, stroke recurrence rate was significantly higher in patients with enlarged LA (LAVI >28 mm3/m2; P <.001 by the log-rank test), and it remained significant in multivariate analysis (hazard ratio, 1.154; 95% confidence interval [CI], 1.099-1.212, P <.001). Conclusions In patients with acute ischemic stroke and NSAT, enlarged LA predicts an increased risk of stroke recurrence. This study supports the necessity of prolonged rhythm monitoring in stroke patients with NSAT and enlarged LA to detect undiagnosed AF and consequently considering anticoagulation therapy.

AB - Background Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF. Methods We investigated the risk factors for predicting the stroke recurrence in NSAT patients. In total, 252 patients (114 women, mean 70 ± 11 years) with acute ischemic stroke and documented NSAT in 24-hour Holter monitoring were enrolled and followed. All patients underwent echo-Doppler evaluations. Results During a mean follow-up period of 35 ± 31 months, the stroke recurrence rate was 11.1% (28 of 252). The patients with recurrence (n = 28) had higher left atrium volume index (LAVI, P <.001) and higher E/e' (P =.028) compared with those without recurrence (n = 224). On the Kaplan-Meier survival analysis, stroke recurrence rate was significantly higher in patients with enlarged LA (LAVI >28 mm3/m2; P <.001 by the log-rank test), and it remained significant in multivariate analysis (hazard ratio, 1.154; 95% confidence interval [CI], 1.099-1.212, P <.001). Conclusions In patients with acute ischemic stroke and NSAT, enlarged LA predicts an increased risk of stroke recurrence. This study supports the necessity of prolonged rhythm monitoring in stroke patients with NSAT and enlarged LA to detect undiagnosed AF and consequently considering anticoagulation therapy.

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