Left ventricular remodeling can be predicted with left ventricular volume response during dobutamine echocardiography after acute myocardial infarction

Se Joong Rim, Jong Won Ha, Moon Hyoung Lee, Yangsoo Jang, Namsik Chung

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives: This study was performed to evaluate the significance of left ventricular (LV) volume response during dobutamine stress echocardiography (DSE) in the prediction of LV volume change during follow-up (F/U) in patients with acute myocardial infarction (AMI). Methods: Forty-five patients with AMI (male 39, age 57±10 y, anterior myocardial infarction [MI] 29) underwent DSE 6±4 d after AMI. Revascularization of the infarct-related artery was performed if severe stenosis was present, A F/U echocardiography was performed 7.5±3.4 mo after DSE. The LV end-diastolic volume (EDV) and end-systolic volume (ESV) using the modified Simpson's method were measured at baseline echocardiography, low-dose (10 μg x kg-1 x min-1) DSE, and F/U echocardiography. Results: Patients were divided into 2 groups; Group I (n = 21) with an abnormal response (<10% decrease) in LVEDV during low-dose DSE; Group II (n = 24) with a normal response (≥10% decrease) in LVEDV during low-dose DSE. At F/U echocardiography, the (%) change of LVEDV was significantly different between the 2 groups (-2.0±16.7 versus -22.6±24.7%, p<0.01). Using multivariate analysis, the response of LVEDV (%) at low-dose DSE was the only significant independent predictor of the change of LVEDV (%) during F/U (y = 0.85 x = 0.08, r = 0.63, p<0.001). Conclusions: The response of LVEDV during DSE can be used as a predictor for the LV volume change after AMI.

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalClinical Cardiology
Volume31
Issue number6
DOIs
Publication statusPublished - 2008 Jun 1

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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