Lessons from an Analysis of Newborn Hearing Screening Data for Children with Cochlear Implants

Jeon Mi Lee, Hyun Jin Lee, Jinsei Jung, InSeok Moon, Sung Huhn Kim, Jin Kim, Jae Young Choi

Research output: Contribution to journalArticle

Abstract

Objectives: The aims of the study are to identify the limitations of the current newborn hearing screening (NHS) programs and provide recommendations for better protocols. Study Design: Retrospective analysis. Setting: Tertiary referral center. Patients: The study participants were 185 children who received cochlear implants (CIs) at ≤5 years of age. Interventions: Therapeutic and rehabilitative. Main Outcome Measures: The results of NHS, screening tools used, age, and hearing thresholds at which hearing loss was confirmed, causes of the hearing loss, age of CI insertion, aided pure-tone audiogram findings, and language development level were analyzed. Results: NHS data was available for 109 children, and 24 patients (22.0%) had passed NHS for both ears. Hearing loss was confirmed considerably later in children who had passed NHS than in children who were referred for further evaluation (p < 0.01). The most common cause for hearing loss in the NHS-pass group was SLC26A4 mutations (41.7%). Patients in the NHS-pass group received CIs considerably later than those in the NHS-referred group (p < 0.01). Among patients with SLC26A4 mutations, the language development level was significantly lower in the NHS-pass group than in the NHS-referred group (p < 0.01). Conclusions: Careful counseling regarding NHS results is necessary for parents to understand that the absence of hearing loss at birth does not mean that the child will not develop hearing loss later in life. Genetic testing for SLC26A4 mutations may be necessary in regions with a high incidence of these mutations, such as East Asia.

Original languageEnglish
Pages (from-to)E909-E917
JournalOtology and Neurotology
Volume40
Issue number9
DOIs
Publication statusPublished - 2019 Oct 1

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Cochlear Implants
Hearing
Newborn Infant
Hearing Loss
Language Development
Mutation
Far East
Genetic Testing
Tertiary Care Centers
Ear
Counseling
Retrospective Studies
Parents
Outcome Assessment (Health Care)
Parturition

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Sensory Systems
  • Clinical Neurology

Cite this

Lee, Jeon Mi ; Lee, Hyun Jin ; Jung, Jinsei ; Moon, InSeok ; Kim, Sung Huhn ; Kim, Jin ; Choi, Jae Young. / Lessons from an Analysis of Newborn Hearing Screening Data for Children with Cochlear Implants. In: Otology and Neurotology. 2019 ; Vol. 40, No. 9. pp. E909-E917.
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abstract = "Objectives: The aims of the study are to identify the limitations of the current newborn hearing screening (NHS) programs and provide recommendations for better protocols. Study Design: Retrospective analysis. Setting: Tertiary referral center. Patients: The study participants were 185 children who received cochlear implants (CIs) at ≤5 years of age. Interventions: Therapeutic and rehabilitative. Main Outcome Measures: The results of NHS, screening tools used, age, and hearing thresholds at which hearing loss was confirmed, causes of the hearing loss, age of CI insertion, aided pure-tone audiogram findings, and language development level were analyzed. Results: NHS data was available for 109 children, and 24 patients (22.0{\%}) had passed NHS for both ears. Hearing loss was confirmed considerably later in children who had passed NHS than in children who were referred for further evaluation (p < 0.01). The most common cause for hearing loss in the NHS-pass group was SLC26A4 mutations (41.7{\%}). Patients in the NHS-pass group received CIs considerably later than those in the NHS-referred group (p < 0.01). Among patients with SLC26A4 mutations, the language development level was significantly lower in the NHS-pass group than in the NHS-referred group (p < 0.01). Conclusions: Careful counseling regarding NHS results is necessary for parents to understand that the absence of hearing loss at birth does not mean that the child will not develop hearing loss later in life. Genetic testing for SLC26A4 mutations may be necessary in regions with a high incidence of these mutations, such as East Asia.",
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Lessons from an Analysis of Newborn Hearing Screening Data for Children with Cochlear Implants. / Lee, Jeon Mi; Lee, Hyun Jin; Jung, Jinsei; Moon, InSeok; Kim, Sung Huhn; Kim, Jin; Choi, Jae Young.

In: Otology and Neurotology, Vol. 40, No. 9, 01.10.2019, p. E909-E917.

Research output: Contribution to journalArticle

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AU - Lee, Hyun Jin

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AU - Kim, Sung Huhn

AU - Kim, Jin

AU - Choi, Jae Young

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N2 - Objectives: The aims of the study are to identify the limitations of the current newborn hearing screening (NHS) programs and provide recommendations for better protocols. Study Design: Retrospective analysis. Setting: Tertiary referral center. Patients: The study participants were 185 children who received cochlear implants (CIs) at ≤5 years of age. Interventions: Therapeutic and rehabilitative. Main Outcome Measures: The results of NHS, screening tools used, age, and hearing thresholds at which hearing loss was confirmed, causes of the hearing loss, age of CI insertion, aided pure-tone audiogram findings, and language development level were analyzed. Results: NHS data was available for 109 children, and 24 patients (22.0%) had passed NHS for both ears. Hearing loss was confirmed considerably later in children who had passed NHS than in children who were referred for further evaluation (p < 0.01). The most common cause for hearing loss in the NHS-pass group was SLC26A4 mutations (41.7%). Patients in the NHS-pass group received CIs considerably later than those in the NHS-referred group (p < 0.01). Among patients with SLC26A4 mutations, the language development level was significantly lower in the NHS-pass group than in the NHS-referred group (p < 0.01). Conclusions: Careful counseling regarding NHS results is necessary for parents to understand that the absence of hearing loss at birth does not mean that the child will not develop hearing loss later in life. Genetic testing for SLC26A4 mutations may be necessary in regions with a high incidence of these mutations, such as East Asia.

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