Light forces the pace: Optical manipulation for biophotonics

David James Stevenson, Frank Gunn-Moore, Kishan Dholakia

Research output: Contribution to journalReview articlepeer-review


The biomedical sciences have benefited immensely from photonics technologies in the last 50years. This includes the application of minute forces that enable the trapping and manipulation of cells and single molecules. In terms of the area of biophotonics, optical manipulation has made a seminal contribution to our understanding of the dynamics of single molecules and the microrheology of cells. Here we present a review of optical manipulation, emphasizing its impact on the areas of single-molecule studies and single-cell biology, and indicating some of the key experiments in the fields.

Original languageEnglish
Article number010808
JournalSPIE Reviews
Issue number1
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering


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