Limited efficacy of uterine artery embolization for cervical leiomyomas

Man Deuk Kim, Myungsu Lee, Dae Chul Jung, Sung Il Park, Mu Sook Lee, Jong Yun Won, Do Yun Lee, Kwang Hun Lee

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Purpose: To explore the effectiveness of uterine artery embolization (UAE) in treating symptomatic fibroids in the uterine cervix. Materials and Methods: Among 537 patients who underwent UAE, 10 who had fibroids located in the cervix were retrospectively analyzed. The mean diameter of the fibroids was 6.0 cm. Seven of the 10 patients presented a total of 10 fibroids in the uterine body or fundus simultaneously. Fibroids of the cervix and fibroids in the body or fundus were compared in terms of the effects of UAE on the treatment thereof and vascularity on angiographic findings. Cervical leiomyomas were classified into three grades based on the vascularity seen on aortography, from grade I, indicating poor vascularity, to grade III, indicating hypervascularity. Necrosis of fibroids was assessed by magnetic resonance imaging 3 months after UAE. Results: Complete necrosis of leiomyomas in the uterine cervix was seen in only two of the 10 patients (20%), whereas all fibroids in the uterine body or fundus were completely infarcted (P <.05). Partial necrosis (PN) of the fibroid with a thin viable rim was seen in two patients, whereas PN with a thick rim was seen in four and no necrosis was seen in two. Grade I (ie, poor) vascularity was noted in five of nine patients (55.6%) with cervical fibroids larger than 3 cm. Conclusions: Poor vascularity was a frequent finding among cervical leiomyomas, and the outcomes of UAE for cervical leiomyomas were disappointing, indicating a need for caution in selecting and counseling patients for this treatment.

Original languageEnglish
Pages (from-to)236-240
Number of pages5
JournalJournal of Vascular and Interventional Radiology
Volume23
Issue number2
DOIs
Publication statusPublished - 2012 Feb 1

Fingerprint

Uterine Artery Embolization
Leiomyoma
Necrosis
Cervix Uteri
Aortography

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Kim, Man Deuk ; Lee, Myungsu ; Jung, Dae Chul ; Park, Sung Il ; Lee, Mu Sook ; Won, Jong Yun ; Lee, Do Yun ; Lee, Kwang Hun. / Limited efficacy of uterine artery embolization for cervical leiomyomas. In: Journal of Vascular and Interventional Radiology. 2012 ; Vol. 23, No. 2. pp. 236-240.
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abstract = "Purpose: To explore the effectiveness of uterine artery embolization (UAE) in treating symptomatic fibroids in the uterine cervix. Materials and Methods: Among 537 patients who underwent UAE, 10 who had fibroids located in the cervix were retrospectively analyzed. The mean diameter of the fibroids was 6.0 cm. Seven of the 10 patients presented a total of 10 fibroids in the uterine body or fundus simultaneously. Fibroids of the cervix and fibroids in the body or fundus were compared in terms of the effects of UAE on the treatment thereof and vascularity on angiographic findings. Cervical leiomyomas were classified into three grades based on the vascularity seen on aortography, from grade I, indicating poor vascularity, to grade III, indicating hypervascularity. Necrosis of fibroids was assessed by magnetic resonance imaging 3 months after UAE. Results: Complete necrosis of leiomyomas in the uterine cervix was seen in only two of the 10 patients (20{\%}), whereas all fibroids in the uterine body or fundus were completely infarcted (P <.05). Partial necrosis (PN) of the fibroid with a thin viable rim was seen in two patients, whereas PN with a thick rim was seen in four and no necrosis was seen in two. Grade I (ie, poor) vascularity was noted in five of nine patients (55.6{\%}) with cervical fibroids larger than 3 cm. Conclusions: Poor vascularity was a frequent finding among cervical leiomyomas, and the outcomes of UAE for cervical leiomyomas were disappointing, indicating a need for caution in selecting and counseling patients for this treatment.",
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Limited efficacy of uterine artery embolization for cervical leiomyomas. / Kim, Man Deuk; Lee, Myungsu; Jung, Dae Chul; Park, Sung Il; Lee, Mu Sook; Won, Jong Yun; Lee, Do Yun; Lee, Kwang Hun.

In: Journal of Vascular and Interventional Radiology, Vol. 23, No. 2, 01.02.2012, p. 236-240.

Research output: Contribution to journalArticle

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