Long-term ambient air pollution and lung function impairment in Chinese children from a high air pollution range area: The Seven Northeastern Cities (SNEC) study

Xiao Wen Zeng, Elaina Vivian, Kahee A. Mohammed, Shailja Jakhar, Michael Vaughn, Jin Huang, Alan Zelicoff, Pamela Xaverius, Zhipeng Bai, Shao Lin, Yuan Tao Hao, Gunther Paul, Lidia Morawska, Si Quan Wang, Zhengmin Qian, Guang Hui Dong

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Epidemiological studies have reported inconsistent and inconclusive associations between long-term exposure to ambient air pollution and lung function in children from Europe and America, where air pollution levels were typically low. The aim of the present study is to examine the relationship between air pollutants and lung function in children selected from heavily industrialized and polluted cities in northeastern China. During 2012, 6740 boys and girls aged 7-14 years were recruited in 24 districts of seven northeastern cities. Portable electronic spirometers were used to measure lung function. Four-year average concentrations of particulate matter with an aerodynamic diameter ≤10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), and ozone (O3) were measured at monitoring stations in the 24 districts. Two-staged regression models were used in the data analysis, controlling for covariates. Overall, for all subjects, the increased odds of lung function impairment associated with exposure to air pollutants, ranged from 5% (adjusted odds ratio [aOR] = 1.05; 95% confidence interval [CI] = 1.01, 1.10) for FVC < 85% predicted per 46.3 μg/m3 for O3 to 81% (aOR = 1.81; 95%CI = 1.44, 2.28) for FEV1 < 85% predicted per 30.6 μg/m3 for PM10. The linear regression models consistently showed a negative relationship between all air pollutants and lung function measures across subjects. There were significant interaction terms indicating gender differences for lung function impairment and pulmonary function from exposure to some pollutants (P < 0.10). In conclusion, long term exposure to high concentrations of ambient air pollution is associated with decreased pulmonary function and lung function impairment, and females appear to be more susceptible than males.

Original languageEnglish
Pages (from-to)144-151
Number of pages8
JournalAtmospheric Environment
Volume138
DOIs
Publication statusPublished - 2016 Aug 1

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)
  • Atmospheric Science

Fingerprint Dive into the research topics of 'Long-term ambient air pollution and lung function impairment in Chinese children from a high air pollution range area: The Seven Northeastern Cities (SNEC) study'. Together they form a unique fingerprint.

  • Cite this

    Zeng, X. W., Vivian, E., Mohammed, K. A., Jakhar, S., Vaughn, M., Huang, J., Zelicoff, A., Xaverius, P., Bai, Z., Lin, S., Hao, Y. T., Paul, G., Morawska, L., Wang, S. Q., Qian, Z., & Dong, G. H. (2016). Long-term ambient air pollution and lung function impairment in Chinese children from a high air pollution range area: The Seven Northeastern Cities (SNEC) study. Atmospheric Environment, 138, 144-151. https://doi.org/10.1016/j.atmosenv.2016.05.003