Long-Term Exposure to Air Pollutants and Cancer Mortality: A Meta-Analysis of Cohort Studies

Hong Bae Kim, Jae Yong Shim, Byoungjin Park, Yong Jae Lee

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The aim of this study was to examine the relationship between main air pollutants and all cancer mortality by performing a meta-analysis. We searched PubMed, EMBASE (a biomedical and pharmacological bibliographic database of published literature produced by Elsevier), and the reference lists of other reviews until April 2018. A random-effects model was employed to analyze the meta-estimates of each pollutant. A total of 30 cohort studies were included in the final analysis. Overall risk estimates of cancer mortality for 10 µg/m³ per increase of particulate matter (PM)2.5, PM10, and NO₂ were 1.17 (95% confidence interval (CI): 1.11⁻1.24), 1.09 (95% CI: 1.04⁻1.14), and 1.06 (95% CI: 1.02⁻1.10), respectively. With respect to the type of cancer, significant hazardous influences of PM2.5 were noticed for lung cancer mortality and non-lung cancer mortality including liver cancer, colorectal cancer, bladder cancer, and kidney cancer, respectively, while PM10 had harmful effects on mortality from lung cancer, pancreas cancer, and larynx cancer. Our meta-analysis of cohort studies indicates that exposure to the main air pollutants is associated with increased mortality from all cancers.

Original languageEnglish
JournalInternational journal of environmental research and public health
Volume15
Issue number11
DOIs
Publication statusPublished - 2018 Nov 21

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Air Pollutants
Meta-Analysis
Cohort Studies
Mortality
Neoplasms
Laryngeal Neoplasms
Kidney Neoplasms
Confidence Intervals
Pancreatic Neoplasms
Urinary Bladder Neoplasms
Lung Neoplasms
Bibliographic Databases
Particulate Matter
Liver Neoplasms
PubMed
Colorectal Neoplasms
Pharmacology

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

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Long-Term Exposure to Air Pollutants and Cancer Mortality : A Meta-Analysis of Cohort Studies. / Kim, Hong Bae; Shim, Jae Yong; Park, Byoungjin; Lee, Yong Jae.

In: International journal of environmental research and public health, Vol. 15, No. 11, 21.11.2018.

Research output: Contribution to journalArticle

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