Abstract
Background: Self-expandable metal stents (SEMSs) provide a promising alternative for initial palliation of malignant bowel obstruction. However, data on the long-term outcomes of SEMSs are limited. Objective: The aim of this study was to compare the long-term outcomes of endoscopic stenting with those of surgery for palliation in patients with incurable obstructive colorectal cancer. Designs and Setting: A retrospective study. Patients: From January 2000 to December 2008, patients with incurable obstructive colorectal cancer who were treated with SEMSs (n = 71) or palliative surgery (n = 73) were reviewed. Interventions: SEMS placement by using through-the-endoscope methods or surgery. Main Outcome Measurements: Success rates and complication rates. Results: Early success rates in the SEMS group and those in the surgery group were not different (95.8% vs 100%, P = .12), and the SEMS group had fewer early complications than the surgery group (15.5% vs 32.9%, P = .015). Although the patency duration of the first stent in the SEMS group was shorter than that in the surgery group (P < .001), the median patency duration after a second stenting was comparable to that of the surgery group (P = .239). There were more late complications in the SEMS group than in the surgery group (P = .028), but the rates of major complications did not differ between the 2 groups (P = .074). Limitations: Retrospective and single-center study. Conclusions: SEMSs were not only an effective and acceptable therapy for initial palliation of malignant colorectal obstruction, but they also showed long-term efficacy comparable to that with surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 535-542 |
| Number of pages | 8 |
| Journal | Gastrointestinal Endoscopy |
| Volume | 73 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2011 Mar 1 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Gastroenterology
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Long-term outcome of palliative therapy for malignant colorectal obstruction in patients with unresectable metastatic colorectal cancers : Endoscopic stenting versus surgery. / Lee, Hyun Jung; Hong, Sung Pil; Cheon, Jae Hee; Kim, Tae Il; Min, Byung So; Kim, Nam Kyu; Kim, Won Ho.
In: Gastrointestinal Endoscopy, Vol. 73, No. 3, 01.03.2011, p. 535-542.Research output: Contribution to journal › Article
TY - JOUR
T1 - Long-term outcome of palliative therapy for malignant colorectal obstruction in patients with unresectable metastatic colorectal cancers
T2 - Endoscopic stenting versus surgery
AU - Lee, Hyun Jung
AU - Hong, Sung Pil
AU - Cheon, Jae Hee
AU - Kim, Tae Il
AU - Min, Byung So
AU - Kim, Nam Kyu
AU - Kim, Won Ho
PY - 2011/3/1
Y1 - 2011/3/1
N2 - Background: Self-expandable metal stents (SEMSs) provide a promising alternative for initial palliation of malignant bowel obstruction. However, data on the long-term outcomes of SEMSs are limited. Objective: The aim of this study was to compare the long-term outcomes of endoscopic stenting with those of surgery for palliation in patients with incurable obstructive colorectal cancer. Designs and Setting: A retrospective study. Patients: From January 2000 to December 2008, patients with incurable obstructive colorectal cancer who were treated with SEMSs (n = 71) or palliative surgery (n = 73) were reviewed. Interventions: SEMS placement by using through-the-endoscope methods or surgery. Main Outcome Measurements: Success rates and complication rates. Results: Early success rates in the SEMS group and those in the surgery group were not different (95.8% vs 100%, P = .12), and the SEMS group had fewer early complications than the surgery group (15.5% vs 32.9%, P = .015). Although the patency duration of the first stent in the SEMS group was shorter than that in the surgery group (P < .001), the median patency duration after a second stenting was comparable to that of the surgery group (P = .239). There were more late complications in the SEMS group than in the surgery group (P = .028), but the rates of major complications did not differ between the 2 groups (P = .074). Limitations: Retrospective and single-center study. Conclusions: SEMSs were not only an effective and acceptable therapy for initial palliation of malignant colorectal obstruction, but they also showed long-term efficacy comparable to that with surgery.
AB - Background: Self-expandable metal stents (SEMSs) provide a promising alternative for initial palliation of malignant bowel obstruction. However, data on the long-term outcomes of SEMSs are limited. Objective: The aim of this study was to compare the long-term outcomes of endoscopic stenting with those of surgery for palliation in patients with incurable obstructive colorectal cancer. Designs and Setting: A retrospective study. Patients: From January 2000 to December 2008, patients with incurable obstructive colorectal cancer who were treated with SEMSs (n = 71) or palliative surgery (n = 73) were reviewed. Interventions: SEMS placement by using through-the-endoscope methods or surgery. Main Outcome Measurements: Success rates and complication rates. Results: Early success rates in the SEMS group and those in the surgery group were not different (95.8% vs 100%, P = .12), and the SEMS group had fewer early complications than the surgery group (15.5% vs 32.9%, P = .015). Although the patency duration of the first stent in the SEMS group was shorter than that in the surgery group (P < .001), the median patency duration after a second stenting was comparable to that of the surgery group (P = .239). There were more late complications in the SEMS group than in the surgery group (P = .028), but the rates of major complications did not differ between the 2 groups (P = .074). Limitations: Retrospective and single-center study. Conclusions: SEMSs were not only an effective and acceptable therapy for initial palliation of malignant colorectal obstruction, but they also showed long-term efficacy comparable to that with surgery.
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UR - http://www.scopus.com/inward/citedby.url?scp=79952068247&partnerID=8YFLogxK
U2 - 10.1016/j.gie.2010.10.052
DO - 10.1016/j.gie.2010.10.052
M3 - Article
C2 - 21257165
AN - SCOPUS:79952068247
VL - 73
SP - 535
EP - 542
JO - Gastrointestinal Endoscopy
JF - Gastrointestinal Endoscopy
SN - 0016-5107
IS - 3
ER -