Long-term outcomes of obscure gastrointestinal bleeding after CT enterography: Does negative CT enterography predict lower long-term rebleeding rate?

Jae Kook Shin, Jae Hee Cheon, Joon Seok Lim, Jae Jun Park, Chang Mo Moon, Soung Min Jeon, Jin Ha Lee, Sung Pil Hong, Tae Il Kim, Won Ho Kim

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background and Aim: Computed tomography enterography (CTE) is a promising modality for small bowel imaging. However, the role of CTE in the evaluation of obscure gastrointestinal bleeding (OGIB) has not been established. We investigated the efficacy of CTE in diagnosing OGIB and the long-term outcomes based on CTE findings, with special reference to negative CTE. Methods: A total of 63 consecutive patients who had undergone CTE for OGIB were enrolled, and their pre- and post-CTE clinical data were collected. "Specific treatments" were defined as treatments directly aimed at resolving presumed bleeding causes, including hemostasis and operation, while "non-specific treatments" were defined as symptomatic treatments for anemia. Results: Among 60 patients for whom long-term follow-up data were available, positive lesions were found in 16 patients (26.7%). The overall rebleeding rate was 21.7% during a mean follow up of 17.6±4.7months. There was no significant difference in the cumulative rebleeding rates between patients with positive and negative CTE results (P=0.241). All patients who received specific treatments after CTE did not rebleed (0/8). In positive CTE patients, specific treatments significantly reduced the rebleeding rate (P=0.023). Conclusions: CTE has a high rate of detecting overt OGIB. However, negative CTE results do not predict lower long-term rebleeding, and such patients with OGIB should be closely observed. In patients with positive CTE, more vigorous management significantly reduces the incidence of rebleeding.

Original languageEnglish
Pages (from-to)901-907
Number of pages7
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume26
Issue number5
DOIs
Publication statusPublished - 2011 May

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Tomography
Hemorrhage
Therapeutics
Hemostasis
Anemia
Incidence

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Shin, Jae Kook ; Cheon, Jae Hee ; Lim, Joon Seok ; Park, Jae Jun ; Moon, Chang Mo ; Jeon, Soung Min ; Lee, Jin Ha ; Hong, Sung Pil ; Kim, Tae Il ; Kim, Won Ho. / Long-term outcomes of obscure gastrointestinal bleeding after CT enterography : Does negative CT enterography predict lower long-term rebleeding rate?. In: Journal of Gastroenterology and Hepatology (Australia). 2011 ; Vol. 26, No. 5. pp. 901-907.
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Long-term outcomes of obscure gastrointestinal bleeding after CT enterography : Does negative CT enterography predict lower long-term rebleeding rate? / Shin, Jae Kook; Cheon, Jae Hee; Lim, Joon Seok; Park, Jae Jun; Moon, Chang Mo; Jeon, Soung Min; Lee, Jin Ha; Hong, Sung Pil; Kim, Tae Il; Kim, Won Ho.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 26, No. 5, 05.2011, p. 901-907.

Research output: Contribution to journalArticle

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T1 - Long-term outcomes of obscure gastrointestinal bleeding after CT enterography

T2 - Does negative CT enterography predict lower long-term rebleeding rate?

AU - Shin, Jae Kook

AU - Cheon, Jae Hee

AU - Lim, Joon Seok

AU - Park, Jae Jun

AU - Moon, Chang Mo

AU - Jeon, Soung Min

AU - Lee, Jin Ha

AU - Hong, Sung Pil

AU - Kim, Tae Il

AU - Kim, Won Ho

PY - 2011/5

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N2 - Background and Aim: Computed tomography enterography (CTE) is a promising modality for small bowel imaging. However, the role of CTE in the evaluation of obscure gastrointestinal bleeding (OGIB) has not been established. We investigated the efficacy of CTE in diagnosing OGIB and the long-term outcomes based on CTE findings, with special reference to negative CTE. Methods: A total of 63 consecutive patients who had undergone CTE for OGIB were enrolled, and their pre- and post-CTE clinical data were collected. "Specific treatments" were defined as treatments directly aimed at resolving presumed bleeding causes, including hemostasis and operation, while "non-specific treatments" were defined as symptomatic treatments for anemia. Results: Among 60 patients for whom long-term follow-up data were available, positive lesions were found in 16 patients (26.7%). The overall rebleeding rate was 21.7% during a mean follow up of 17.6±4.7months. There was no significant difference in the cumulative rebleeding rates between patients with positive and negative CTE results (P=0.241). All patients who received specific treatments after CTE did not rebleed (0/8). In positive CTE patients, specific treatments significantly reduced the rebleeding rate (P=0.023). Conclusions: CTE has a high rate of detecting overt OGIB. However, negative CTE results do not predict lower long-term rebleeding, and such patients with OGIB should be closely observed. In patients with positive CTE, more vigorous management significantly reduces the incidence of rebleeding.

AB - Background and Aim: Computed tomography enterography (CTE) is a promising modality for small bowel imaging. However, the role of CTE in the evaluation of obscure gastrointestinal bleeding (OGIB) has not been established. We investigated the efficacy of CTE in diagnosing OGIB and the long-term outcomes based on CTE findings, with special reference to negative CTE. Methods: A total of 63 consecutive patients who had undergone CTE for OGIB were enrolled, and their pre- and post-CTE clinical data were collected. "Specific treatments" were defined as treatments directly aimed at resolving presumed bleeding causes, including hemostasis and operation, while "non-specific treatments" were defined as symptomatic treatments for anemia. Results: Among 60 patients for whom long-term follow-up data were available, positive lesions were found in 16 patients (26.7%). The overall rebleeding rate was 21.7% during a mean follow up of 17.6±4.7months. There was no significant difference in the cumulative rebleeding rates between patients with positive and negative CTE results (P=0.241). All patients who received specific treatments after CTE did not rebleed (0/8). In positive CTE patients, specific treatments significantly reduced the rebleeding rate (P=0.023). Conclusions: CTE has a high rate of detecting overt OGIB. However, negative CTE results do not predict lower long-term rebleeding, and such patients with OGIB should be closely observed. In patients with positive CTE, more vigorous management significantly reduces the incidence of rebleeding.

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