Abstract
Background: To evaluate the long-time progression of retinal vasculitis in Behçet patients using the fluorescein angiography (FA) scoring system. Methods: Retrospective study was conducted for 71 eyes of 43 patients who met the study criteria. All patients completed at least 2 years of follow-up. FA was taken during the periods of active retinal vasculitis and the quiescent phase, and analyzed using a FA scoring system. Among nine categories, the four most prevalent FA signs were evaluated: optic disc hyperfluorescence (score 0-3), macular edema (score 0-4), retinal vascular staining and/or leakage (score 0-7), and capillary leakage (score 0-10). Results: Mean number of total active inflammations was 2.6±1.5 times during mean 55.0±20.0 months. Mean scores at the first active inflammation were 1.8±1.0 for optic disc hyperfluorescence, 2.4±1.0 for macular edema, 5.3±2.1 for retinal vascular staining and/or leakage, and 5.8±3.2 for capillary leakage. Mean total FA score was 17.4±6.8. Mean scores at the first quiescent phase were 0.6±0.4 for optic disc hyperfluorescence, 1.1±1.2 for macular edema, 3.8±1.9 for retinal vascular staining and/or leakage, and 3.5±3.5 for capillary leakage. Mean total FA score was 9.1±5.0. Mean scores for each active inflammation and quiescent phase were not significantly changed, and mean FA scores were significantly reduced in quiescent phase (P=0.003 for optic disc hyperfluorescence, P=0.005 for macular leakage, P=0.010 for retinal vascular staining and/or leakage, P=0.008 for capillary leakage, and P=0.018 for total FA score; paired t-test). Conclusions: Retinal vasculitis of Behçet patients did not significantly progress during long-term follow-up.
| Original language | English |
|---|---|
| Pages (from-to) | 1001-1008 |
| Number of pages | 8 |
| Journal | Graefe's Archive for Clinical and Experimental Ophthalmology |
| Volume | 252 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience
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Long-term progression of retinal vasculitis in Behçet patients using a fluorescein angiography scoring system. / Kang, Hae Min; Lee, Sungchul.
In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 252, No. 6, 01.01.2014, p. 1001-1008.Research output: Contribution to journal › Article
TY - JOUR
T1 - Long-term progression of retinal vasculitis in Behçet patients using a fluorescein angiography scoring system
AU - Kang, Hae Min
AU - Lee, Sungchul
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Background: To evaluate the long-time progression of retinal vasculitis in Behçet patients using the fluorescein angiography (FA) scoring system. Methods: Retrospective study was conducted for 71 eyes of 43 patients who met the study criteria. All patients completed at least 2 years of follow-up. FA was taken during the periods of active retinal vasculitis and the quiescent phase, and analyzed using a FA scoring system. Among nine categories, the four most prevalent FA signs were evaluated: optic disc hyperfluorescence (score 0-3), macular edema (score 0-4), retinal vascular staining and/or leakage (score 0-7), and capillary leakage (score 0-10). Results: Mean number of total active inflammations was 2.6±1.5 times during mean 55.0±20.0 months. Mean scores at the first active inflammation were 1.8±1.0 for optic disc hyperfluorescence, 2.4±1.0 for macular edema, 5.3±2.1 for retinal vascular staining and/or leakage, and 5.8±3.2 for capillary leakage. Mean total FA score was 17.4±6.8. Mean scores at the first quiescent phase were 0.6±0.4 for optic disc hyperfluorescence, 1.1±1.2 for macular edema, 3.8±1.9 for retinal vascular staining and/or leakage, and 3.5±3.5 for capillary leakage. Mean total FA score was 9.1±5.0. Mean scores for each active inflammation and quiescent phase were not significantly changed, and mean FA scores were significantly reduced in quiescent phase (P=0.003 for optic disc hyperfluorescence, P=0.005 for macular leakage, P=0.010 for retinal vascular staining and/or leakage, P=0.008 for capillary leakage, and P=0.018 for total FA score; paired t-test). Conclusions: Retinal vasculitis of Behçet patients did not significantly progress during long-term follow-up.
AB - Background: To evaluate the long-time progression of retinal vasculitis in Behçet patients using the fluorescein angiography (FA) scoring system. Methods: Retrospective study was conducted for 71 eyes of 43 patients who met the study criteria. All patients completed at least 2 years of follow-up. FA was taken during the periods of active retinal vasculitis and the quiescent phase, and analyzed using a FA scoring system. Among nine categories, the four most prevalent FA signs were evaluated: optic disc hyperfluorescence (score 0-3), macular edema (score 0-4), retinal vascular staining and/or leakage (score 0-7), and capillary leakage (score 0-10). Results: Mean number of total active inflammations was 2.6±1.5 times during mean 55.0±20.0 months. Mean scores at the first active inflammation were 1.8±1.0 for optic disc hyperfluorescence, 2.4±1.0 for macular edema, 5.3±2.1 for retinal vascular staining and/or leakage, and 5.8±3.2 for capillary leakage. Mean total FA score was 17.4±6.8. Mean scores at the first quiescent phase were 0.6±0.4 for optic disc hyperfluorescence, 1.1±1.2 for macular edema, 3.8±1.9 for retinal vascular staining and/or leakage, and 3.5±3.5 for capillary leakage. Mean total FA score was 9.1±5.0. Mean scores for each active inflammation and quiescent phase were not significantly changed, and mean FA scores were significantly reduced in quiescent phase (P=0.003 for optic disc hyperfluorescence, P=0.005 for macular leakage, P=0.010 for retinal vascular staining and/or leakage, P=0.008 for capillary leakage, and P=0.018 for total FA score; paired t-test). Conclusions: Retinal vasculitis of Behçet patients did not significantly progress during long-term follow-up.
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U2 - 10.1007/s00417-014-2637-z
DO - 10.1007/s00417-014-2637-z
M3 - Article
C2 - 24796770
AN - SCOPUS:84902239603
VL - 252
SP - 1001
EP - 1008
JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
SN - 0065-6100
IS - 6
ER -