Looking at the self in front of others: Neural correlates of attentional bias in social anxiety

Soo Hee Choi, Jung Eun Shin, Jeonghun Ku, Jae Jin Kim

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In social anxiety disorder (SAD), anxiety reactions are triggered by attentional bias to social threats that automatically appear in social situations. The present study aimed to investigate the neural basis and underlying resting-state pathology of attentional bias toward internal and external social threats as a core element of SAD. Twenty-two patients with SAD and 20 control subjects scanned functional magnetic resonance imaging during resting-state and while performing the visual search task. During the task, participants were exposed to internal threat (hearing participants' own pulse-sounds) and external threat (crowds in facial matrices). Patients showed activations in the lateral orbitofrontal cortex, rostral anterior cingulate cortex and insula in response to internal threat and activations in the posterior cingulate cortex and middle temporal gyrus in response to external threat. In patients, neural activity related to combined internal and external threats in the posterior cingulate cortex was inversely correlated with the functional connectivity strengths with the default mode network during resting-state. These findings suggest that attentional bias may stem from limbic and paralimbic pathology, and the interactive process of internally- and externally-focused attentional bias in SAD is associated with the self-referential function of resting-state.

Original languageEnglish
Pages (from-to)31-40
Number of pages10
JournalJournal of Psychiatric Research
Volume75
DOIs
Publication statusPublished - 2016 Apr 1

Fingerprint

Gyrus Cinguli
Anxiety
Pathology
Temporal Lobe
Prefrontal Cortex
Hearing
Magnetic Resonance Imaging
Attentional Bias
Social Phobia

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

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abstract = "In social anxiety disorder (SAD), anxiety reactions are triggered by attentional bias to social threats that automatically appear in social situations. The present study aimed to investigate the neural basis and underlying resting-state pathology of attentional bias toward internal and external social threats as a core element of SAD. Twenty-two patients with SAD and 20 control subjects scanned functional magnetic resonance imaging during resting-state and while performing the visual search task. During the task, participants were exposed to internal threat (hearing participants' own pulse-sounds) and external threat (crowds in facial matrices). Patients showed activations in the lateral orbitofrontal cortex, rostral anterior cingulate cortex and insula in response to internal threat and activations in the posterior cingulate cortex and middle temporal gyrus in response to external threat. In patients, neural activity related to combined internal and external threats in the posterior cingulate cortex was inversely correlated with the functional connectivity strengths with the default mode network during resting-state. These findings suggest that attentional bias may stem from limbic and paralimbic pathology, and the interactive process of internally- and externally-focused attentional bias in SAD is associated with the self-referential function of resting-state.",
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Looking at the self in front of others : Neural correlates of attentional bias in social anxiety. / Choi, Soo Hee; Shin, Jung Eun; Ku, Jeonghun; Kim, Jae Jin.

In: Journal of Psychiatric Research, Vol. 75, 01.04.2016, p. 31-40.

Research output: Contribution to journalArticle

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