Lower-fluence, higher-density versus higher-fluence, lower-density treatment with a 10,600-nm carbon dioxide fractional laser system

A split-face, evaluator-blinded study

Jin Young Jung, JuHee Lee, Dong Jin Ryu, Sang Ju Lee, Dongsik Bang, Sung Bin Cho

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background Adequate laser settings in the treatment of scars using a carbon dioxide fractional laser system (CO 2 FS) have not been established. Objective To compare the efficacy and safety of low-fluence, high-density with high-fluence, low-density treatment with CO 2 FS on acne scars and enlarged pores. Methods Ten patients with mild to severe atrophic acne scars and enlarged pores were enrolled. Half of each subject's face was treated with a single session of CO 2 FS with a fluence of 70 mJ and a density of 150 spots/cm 2 ; the other half was treated with a fluence of 30 mJ and a density of 250 spots/cm 2 . Results Follow-up results 3 months after a single low-fluence, high-density treatment with CO 2 FS showed that four of 10 participants had clinical improvement of 51% to 75% from baseline. After the high-fluence, low-density CO 2 FS treatment, five of 10 patients demonstrated marked clinical improvements of more than 76%. Conclusion Higher-energy, lower-density laser settings seem to be more effective than lower-energy, higher-density settings for acne scars and enlarged pores, although our results do not constitute a conclusive comparison of the two different modes of CO 2 FS.

Original languageEnglish
Pages (from-to)2022-2029
Number of pages8
JournalDermatologic Surgery
Volume36
Issue number12
DOIs
Publication statusPublished - 2010 Dec 1

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Gas Lasers
Carbon Monoxide
Cicatrix
Acne Vulgaris
Lasers
Therapeutics
Safety

All Science Journal Classification (ASJC) codes

  • Surgery
  • Dermatology

Cite this

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title = "Lower-fluence, higher-density versus higher-fluence, lower-density treatment with a 10,600-nm carbon dioxide fractional laser system: A split-face, evaluator-blinded study",
abstract = "Background Adequate laser settings in the treatment of scars using a carbon dioxide fractional laser system (CO 2 FS) have not been established. Objective To compare the efficacy and safety of low-fluence, high-density with high-fluence, low-density treatment with CO 2 FS on acne scars and enlarged pores. Methods Ten patients with mild to severe atrophic acne scars and enlarged pores were enrolled. Half of each subject's face was treated with a single session of CO 2 FS with a fluence of 70 mJ and a density of 150 spots/cm 2 ; the other half was treated with a fluence of 30 mJ and a density of 250 spots/cm 2 . Results Follow-up results 3 months after a single low-fluence, high-density treatment with CO 2 FS showed that four of 10 participants had clinical improvement of 51{\%} to 75{\%} from baseline. After the high-fluence, low-density CO 2 FS treatment, five of 10 patients demonstrated marked clinical improvements of more than 76{\%}. Conclusion Higher-energy, lower-density laser settings seem to be more effective than lower-energy, higher-density settings for acne scars and enlarged pores, although our results do not constitute a conclusive comparison of the two different modes of CO 2 FS.",
author = "Jung, {Jin Young} and JuHee Lee and Ryu, {Dong Jin} and Lee, {Sang Ju} and Dongsik Bang and Cho, {Sung Bin}",
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Lower-fluence, higher-density versus higher-fluence, lower-density treatment with a 10,600-nm carbon dioxide fractional laser system : A split-face, evaluator-blinded study. / Jung, Jin Young; Lee, JuHee; Ryu, Dong Jin; Lee, Sang Ju; Bang, Dongsik; Cho, Sung Bin.

In: Dermatologic Surgery, Vol. 36, No. 12, 01.12.2010, p. 2022-2029.

Research output: Contribution to journalArticle

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AU - Jung, Jin Young

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AU - Ryu, Dong Jin

AU - Lee, Sang Ju

AU - Bang, Dongsik

AU - Cho, Sung Bin

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N2 - Background Adequate laser settings in the treatment of scars using a carbon dioxide fractional laser system (CO 2 FS) have not been established. Objective To compare the efficacy and safety of low-fluence, high-density with high-fluence, low-density treatment with CO 2 FS on acne scars and enlarged pores. Methods Ten patients with mild to severe atrophic acne scars and enlarged pores were enrolled. Half of each subject's face was treated with a single session of CO 2 FS with a fluence of 70 mJ and a density of 150 spots/cm 2 ; the other half was treated with a fluence of 30 mJ and a density of 250 spots/cm 2 . Results Follow-up results 3 months after a single low-fluence, high-density treatment with CO 2 FS showed that four of 10 participants had clinical improvement of 51% to 75% from baseline. After the high-fluence, low-density CO 2 FS treatment, five of 10 patients demonstrated marked clinical improvements of more than 76%. Conclusion Higher-energy, lower-density laser settings seem to be more effective than lower-energy, higher-density settings for acne scars and enlarged pores, although our results do not constitute a conclusive comparison of the two different modes of CO 2 FS.

AB - Background Adequate laser settings in the treatment of scars using a carbon dioxide fractional laser system (CO 2 FS) have not been established. Objective To compare the efficacy and safety of low-fluence, high-density with high-fluence, low-density treatment with CO 2 FS on acne scars and enlarged pores. Methods Ten patients with mild to severe atrophic acne scars and enlarged pores were enrolled. Half of each subject's face was treated with a single session of CO 2 FS with a fluence of 70 mJ and a density of 150 spots/cm 2 ; the other half was treated with a fluence of 30 mJ and a density of 250 spots/cm 2 . Results Follow-up results 3 months after a single low-fluence, high-density treatment with CO 2 FS showed that four of 10 participants had clinical improvement of 51% to 75% from baseline. After the high-fluence, low-density CO 2 FS treatment, five of 10 patients demonstrated marked clinical improvements of more than 76%. Conclusion Higher-energy, lower-density laser settings seem to be more effective than lower-energy, higher-density settings for acne scars and enlarged pores, although our results do not constitute a conclusive comparison of the two different modes of CO 2 FS.

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