Lymphocele after extraperitoneal robot-assisted radical prostatectomy

A propensity score-matching study

Joo Yong Lee, Richilda Red Diaz, Kang Su Cho, Ho Song Yu, Jae Seung Chung, Won Sik Ham, Youngdeuk Choi

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objectives: To investigate the incidence of lymphocele and determine the risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy by using propensity score-matching. Methods: A total of 483 patients underwent extraperitoneal robot-assisted radical prostatectomy for prostate cancer between January 2009 and August 2011. Of these, 200 patients underwent pelvic lymph node dissection during robot-assisted radical prostatectomy. All patients underwent magnetic resonance imaging or computed tomography postoperatively to detect lymphocele after robot-assisted radical prostatectomy. Propensity scores for an established control group were calculated for each patient using multivariate logistic regression based on the following covariates: age, body mass index, preoperative prostate-specific antigen level, prostate volume calculated by transrectal ultrasound, biopsy Gleason sum and clinical tumor stage. Results: Lymphocele was identified in 41 patients (20.5%). There were no statistical differences in variables used in propensity score-matching. Operation time, estimated blood loss, catheterization and surgical margin positivity did not show differences between the two groups. Seminal vesicle invasion (P=0.015) and tumor volume (P=0.042) between the two groups were significantly different. In the multivariate logistic regression model, extracapsular extension (P=0.017, odds ratio 4.231), seminal vesicle invasion (P=0.028, odds ratio 2.643) and the number of positive lymph nodes (P=0.041, odds ratio 3.532) were independent risk factors for lymphocele development after extraperitoneal robot-assisted radical prostatectomy with pelvic lymph node dissection. Conclusions: Lymphocele might preferentially develop in cases with seminal vesicle invasion and large tumor volume. Additionally, extracapsular extension, seminal vesicle invasion, and the number of positive lymph nodes are independent risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy.

Original languageEnglish
Pages (from-to)1169-1176
Number of pages8
JournalInternational Journal of Urology
Volume20
Issue number12
DOIs
Publication statusPublished - 2013 Jan 1

Fingerprint

Lymphocele
Propensity Score
Prostatectomy
Seminal Vesicles
Logistic Models
Odds Ratio
Tumor Burden
Lymph Node Excision
Lymph Nodes
Prostate-Specific Antigen
Catheterization
Prostate
Prostatic Neoplasms
Body Mass Index
Tomography
Magnetic Resonance Imaging
Biopsy
Control Groups
Incidence

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Lee, Joo Yong ; Diaz, Richilda Red ; Cho, Kang Su ; Yu, Ho Song ; Chung, Jae Seung ; Ham, Won Sik ; Choi, Youngdeuk. / Lymphocele after extraperitoneal robot-assisted radical prostatectomy : A propensity score-matching study. In: International Journal of Urology. 2013 ; Vol. 20, No. 12. pp. 1169-1176.
@article{19ff07a49b8b4cf8b9c4f676c9fe41c2,
title = "Lymphocele after extraperitoneal robot-assisted radical prostatectomy: A propensity score-matching study",
abstract = "Objectives: To investigate the incidence of lymphocele and determine the risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy by using propensity score-matching. Methods: A total of 483 patients underwent extraperitoneal robot-assisted radical prostatectomy for prostate cancer between January 2009 and August 2011. Of these, 200 patients underwent pelvic lymph node dissection during robot-assisted radical prostatectomy. All patients underwent magnetic resonance imaging or computed tomography postoperatively to detect lymphocele after robot-assisted radical prostatectomy. Propensity scores for an established control group were calculated for each patient using multivariate logistic regression based on the following covariates: age, body mass index, preoperative prostate-specific antigen level, prostate volume calculated by transrectal ultrasound, biopsy Gleason sum and clinical tumor stage. Results: Lymphocele was identified in 41 patients (20.5{\%}). There were no statistical differences in variables used in propensity score-matching. Operation time, estimated blood loss, catheterization and surgical margin positivity did not show differences between the two groups. Seminal vesicle invasion (P=0.015) and tumor volume (P=0.042) between the two groups were significantly different. In the multivariate logistic regression model, extracapsular extension (P=0.017, odds ratio 4.231), seminal vesicle invasion (P=0.028, odds ratio 2.643) and the number of positive lymph nodes (P=0.041, odds ratio 3.532) were independent risk factors for lymphocele development after extraperitoneal robot-assisted radical prostatectomy with pelvic lymph node dissection. Conclusions: Lymphocele might preferentially develop in cases with seminal vesicle invasion and large tumor volume. Additionally, extracapsular extension, seminal vesicle invasion, and the number of positive lymph nodes are independent risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy.",
author = "Lee, {Joo Yong} and Diaz, {Richilda Red} and Cho, {Kang Su} and Yu, {Ho Song} and Chung, {Jae Seung} and Ham, {Won Sik} and Youngdeuk Choi",
year = "2013",
month = "1",
day = "1",
doi = "10.1111/iju.12144",
language = "English",
volume = "20",
pages = "1169--1176",
journal = "International Journal of Urology",
issn = "0919-8172",
publisher = "Wiley-Blackwell",
number = "12",

}

Lymphocele after extraperitoneal robot-assisted radical prostatectomy : A propensity score-matching study. / Lee, Joo Yong; Diaz, Richilda Red; Cho, Kang Su; Yu, Ho Song; Chung, Jae Seung; Ham, Won Sik; Choi, Youngdeuk.

In: International Journal of Urology, Vol. 20, No. 12, 01.01.2013, p. 1169-1176.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Lymphocele after extraperitoneal robot-assisted radical prostatectomy

T2 - A propensity score-matching study

AU - Lee, Joo Yong

AU - Diaz, Richilda Red

AU - Cho, Kang Su

AU - Yu, Ho Song

AU - Chung, Jae Seung

AU - Ham, Won Sik

AU - Choi, Youngdeuk

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Objectives: To investigate the incidence of lymphocele and determine the risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy by using propensity score-matching. Methods: A total of 483 patients underwent extraperitoneal robot-assisted radical prostatectomy for prostate cancer between January 2009 and August 2011. Of these, 200 patients underwent pelvic lymph node dissection during robot-assisted radical prostatectomy. All patients underwent magnetic resonance imaging or computed tomography postoperatively to detect lymphocele after robot-assisted radical prostatectomy. Propensity scores for an established control group were calculated for each patient using multivariate logistic regression based on the following covariates: age, body mass index, preoperative prostate-specific antigen level, prostate volume calculated by transrectal ultrasound, biopsy Gleason sum and clinical tumor stage. Results: Lymphocele was identified in 41 patients (20.5%). There were no statistical differences in variables used in propensity score-matching. Operation time, estimated blood loss, catheterization and surgical margin positivity did not show differences between the two groups. Seminal vesicle invasion (P=0.015) and tumor volume (P=0.042) between the two groups were significantly different. In the multivariate logistic regression model, extracapsular extension (P=0.017, odds ratio 4.231), seminal vesicle invasion (P=0.028, odds ratio 2.643) and the number of positive lymph nodes (P=0.041, odds ratio 3.532) were independent risk factors for lymphocele development after extraperitoneal robot-assisted radical prostatectomy with pelvic lymph node dissection. Conclusions: Lymphocele might preferentially develop in cases with seminal vesicle invasion and large tumor volume. Additionally, extracapsular extension, seminal vesicle invasion, and the number of positive lymph nodes are independent risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy.

AB - Objectives: To investigate the incidence of lymphocele and determine the risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy by using propensity score-matching. Methods: A total of 483 patients underwent extraperitoneal robot-assisted radical prostatectomy for prostate cancer between January 2009 and August 2011. Of these, 200 patients underwent pelvic lymph node dissection during robot-assisted radical prostatectomy. All patients underwent magnetic resonance imaging or computed tomography postoperatively to detect lymphocele after robot-assisted radical prostatectomy. Propensity scores for an established control group were calculated for each patient using multivariate logistic regression based on the following covariates: age, body mass index, preoperative prostate-specific antigen level, prostate volume calculated by transrectal ultrasound, biopsy Gleason sum and clinical tumor stage. Results: Lymphocele was identified in 41 patients (20.5%). There were no statistical differences in variables used in propensity score-matching. Operation time, estimated blood loss, catheterization and surgical margin positivity did not show differences between the two groups. Seminal vesicle invasion (P=0.015) and tumor volume (P=0.042) between the two groups were significantly different. In the multivariate logistic regression model, extracapsular extension (P=0.017, odds ratio 4.231), seminal vesicle invasion (P=0.028, odds ratio 2.643) and the number of positive lymph nodes (P=0.041, odds ratio 3.532) were independent risk factors for lymphocele development after extraperitoneal robot-assisted radical prostatectomy with pelvic lymph node dissection. Conclusions: Lymphocele might preferentially develop in cases with seminal vesicle invasion and large tumor volume. Additionally, extracapsular extension, seminal vesicle invasion, and the number of positive lymph nodes are independent risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy.

UR - http://www.scopus.com/inward/record.url?scp=84897102267&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897102267&partnerID=8YFLogxK

U2 - 10.1111/iju.12144

DO - 10.1111/iju.12144

M3 - Article

VL - 20

SP - 1169

EP - 1176

JO - International Journal of Urology

JF - International Journal of Urology

SN - 0919-8172

IS - 12

ER -