BACKGROUND AND OBJECTIVE: To evaluate the association between macular choroidal thickness and the development, progression, and resolution of epiretinal membrane (ERM). PATIENTS AND METHODS: The patients (n = 38) with unilateral ERM eyes with definitive changes on optical coherence tomography (OCT) and healthy fellow eyes were observed retrospectively. ERM eyes were divided into three groups: Development/new-onset group (n = 14), progression group (n = 13), and resolution group (n = 11). In each group, the average changes of macular choroidal thickness over time in ERM eyes were compared with those in the fellow eyes RESULTS: Choroidal thickness significantly decreased from 174.0 μm at baseline to 132.3 μm at event time (P = .001) in the development group, and from 140.0 μm ± 30.0 μm to 120.5 μm (P = .002) in the progression group. Conversely, a significant increase in choroidal thickness was observed in the resolution group (from 205.2 μm to 222.6 μm; P = .004). The fellow eyes showed no significant changes in choroidal thickness in all three groups. CONCLUSION: Choroidal thinning in newly developed or significantly progressed ERM eyes and choroidal thickening in spontaneously resolved ERM eyes suggest a clinical implication of choroidal changes in ERM.
|Number of pages||8|
|Journal||Ophthalmic Surgery Lasers and Imaging Retina|
|Publication status||Published - 2019|
Bibliographical noteFunding Information:
Originally submitted September 12, 2018. Revision received January 10, 2019. Accepted for publication March 11, 2019. Paper presented at the 2017 Korean Retina Society Annual Meeting. Supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (NRF-2016R1D1A1A02937349). The funding organization had no role in the design or conduct of this research. The authors report no relevant financial disclosures. Address correspondence to Christopher Seungkyu Lee, MD, PhD, Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, Korea; email: email@example.com. doi: 10.3928/23258160-20191009-05
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