Macular choroidal thickness changes in development, progression, and spontaneous resolution of epiretinal membrane

Eun Young Choi, Jongwook Han, Sung Chul Lee, Christopher Seungkyu Lee

Research output: Contribution to journalArticle

Abstract

BACKGROUND AND OBJECTIVE: To evaluate the association between macular choroidal thickness and the development, progression, and resolution of epiretinal membrane (ERM). PATIENTS AND METHODS: The patients (n = 38) with unilateral ERM eyes with definitive changes on optical coherence tomography (OCT) and healthy fellow eyes were observed retrospectively. ERM eyes were divided into three groups: Development/new-onset group (n = 14), progression group (n = 13), and resolution group (n = 11). In each group, the average changes of macular choroidal thickness over time in ERM eyes were compared with those in the fellow eyes RESULTS: Choroidal thickness significantly decreased from 174.0 μm at baseline to 132.3 μm at event time (P = .001) in the development group, and from 140.0 μm ± 30.0 μm to 120.5 μm (P = .002) in the progression group. Conversely, a significant increase in choroidal thickness was observed in the resolution group (from 205.2 μm to 222.6 μm; P = .004). The fellow eyes showed no significant changes in choroidal thickness in all three groups. CONCLUSION: Choroidal thinning in newly developed or significantly progressed ERM eyes and choroidal thickening in spontaneously resolved ERM eyes suggest a clinical implication of choroidal changes in ERM.

Original languageEnglish
Pages (from-to)627-634
Number of pages8
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume50
Issue number10
DOIs
Publication statusPublished - 2019 Jan 1

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Epiretinal Membrane
Optical Coherence Tomography

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology

Cite this

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abstract = "BACKGROUND AND OBJECTIVE: To evaluate the association between macular choroidal thickness and the development, progression, and resolution of epiretinal membrane (ERM). PATIENTS AND METHODS: The patients (n = 38) with unilateral ERM eyes with definitive changes on optical coherence tomography (OCT) and healthy fellow eyes were observed retrospectively. ERM eyes were divided into three groups: Development/new-onset group (n = 14), progression group (n = 13), and resolution group (n = 11). In each group, the average changes of macular choroidal thickness over time in ERM eyes were compared with those in the fellow eyes RESULTS: Choroidal thickness significantly decreased from 174.0 μm at baseline to 132.3 μm at event time (P = .001) in the development group, and from 140.0 μm ± 30.0 μm to 120.5 μm (P = .002) in the progression group. Conversely, a significant increase in choroidal thickness was observed in the resolution group (from 205.2 μm to 222.6 μm; P = .004). The fellow eyes showed no significant changes in choroidal thickness in all three groups. CONCLUSION: Choroidal thinning in newly developed or significantly progressed ERM eyes and choroidal thickening in spontaneously resolved ERM eyes suggest a clinical implication of choroidal changes in ERM.",
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Macular choroidal thickness changes in development, progression, and spontaneous resolution of epiretinal membrane. / Choi, Eun Young; Han, Jongwook; Lee, Sung Chul; Lee, Christopher Seungkyu.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 50, No. 10, 01.01.2019, p. 627-634.

Research output: Contribution to journalArticle

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