Magnetic nanoclusters for ultrasensitive magnetophoretic assays

Zongwen Jin, Young Ki Hahn, Eunkeu Oh, Young Pil Kim, Je Kyun Park, Seung Ho Moon, Jung Tak Jang, Jinwoo Cheon, Hak Sung Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Magnetic nanoclusters (MNCs) are developed and used for an ultrasensitive magnetophoretic assay system. Prostate-specific antigen (PSA) is used as a target analyte (see image). The deflection velocity of a microbead is well correlated with the PSA concentration, with a detection limit of 45 fg mL -1 , and this value is three orders of magnitude higher than conventional ELISA. The developed assay format is expected to be effectively applied to the detection of a target analyte with low abundance.

Original languageEnglish
Pages (from-to)2243-2246
Number of pages4
JournalSmall
Volume5
Issue number20
DOIs
Publication statusPublished - 2009 Oct 16

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

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  • Cite this

    Jin, Z., Hahn, Y. K., Oh, E., Kim, Y. P., Park, J. K., Moon, S. H., Jang, J. T., Cheon, J., & Kim, H. S. (2009). Magnetic nanoclusters for ultrasensitive magnetophoretic assays. Small, 5(20), 2243-2246. https://doi.org/10.1002/smll.200900311