Magnetic nanoclusters for ultrasensitive magnetophoretic assays

Zongwen Jin, Young Ki Hahn, Eunkeu Oh, Young Pil Kim, Je Kyun Park, Seung Ho Moon, Jung Tak Jang, Jinwoo Cheon, Hak Sung Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Magnetic nanoclusters (MNCs) are developed and used for an ultrasensitive magnetophoretic assay system. Prostate-specific antigen (PSA) is used as a target analyte (see image). The deflection velocity of a microbead is well correlated with the PSA concentration, with a detection limit of 45 fg mL -1 , and this value is three orders of magnitude higher than conventional ELISA. The developed assay format is expected to be effectively applied to the detection of a target analyte with low abundance.

Original languageEnglish
Pages (from-to)2243-2246
Number of pages4
JournalSmall
Volume5
Issue number20
DOIs
Publication statusPublished - 2009 Oct 16

Fingerprint

Nanoclusters
Prostate-Specific Antigen
Antigens
Assays
Microspheres
Limit of Detection
Enzyme-Linked Immunosorbent Assay

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

Cite this

Jin, Z., Hahn, Y. K., Oh, E., Kim, Y. P., Park, J. K., Moon, S. H., ... Kim, H. S. (2009). Magnetic nanoclusters for ultrasensitive magnetophoretic assays. Small, 5(20), 2243-2246. https://doi.org/10.1002/smll.200900311
Jin, Zongwen ; Hahn, Young Ki ; Oh, Eunkeu ; Kim, Young Pil ; Park, Je Kyun ; Moon, Seung Ho ; Jang, Jung Tak ; Cheon, Jinwoo ; Kim, Hak Sung. / Magnetic nanoclusters for ultrasensitive magnetophoretic assays. In: Small. 2009 ; Vol. 5, No. 20. pp. 2243-2246.
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Jin, Z, Hahn, YK, Oh, E, Kim, YP, Park, JK, Moon, SH, Jang, JT, Cheon, J & Kim, HS 2009, 'Magnetic nanoclusters for ultrasensitive magnetophoretic assays', Small, vol. 5, no. 20, pp. 2243-2246. https://doi.org/10.1002/smll.200900311

Magnetic nanoclusters for ultrasensitive magnetophoretic assays. / Jin, Zongwen; Hahn, Young Ki; Oh, Eunkeu; Kim, Young Pil; Park, Je Kyun; Moon, Seung Ho; Jang, Jung Tak; Cheon, Jinwoo; Kim, Hak Sung.

In: Small, Vol. 5, No. 20, 16.10.2009, p. 2243-2246.

Research output: Contribution to journalArticle

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AU - Jang, Jung Tak

AU - Cheon, Jinwoo

AU - Kim, Hak Sung

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Jin Z, Hahn YK, Oh E, Kim YP, Park JK, Moon SH et al. Magnetic nanoclusters for ultrasensitive magnetophoretic assays. Small. 2009 Oct 16;5(20):2243-2246. https://doi.org/10.1002/smll.200900311