Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

Jaemoon Yang, Jaewon Lee, Jinyoung Kang, Chan Hwa Chung, Kwangyeol Lee, Jinsuck Suh, Ho Geun Yoon, yongmin Huh, Seungjoo Haam

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

Original languageEnglish
Article number075610
JournalNanotechnology
Volume19
Issue number7
DOIs
Publication statusPublished - 2008 Feb 14

Fingerprint

Silicon Dioxide
Silica
Nanoparticles
Magnetic resonance
Fluorescent Dyes
Magnetization
Dyes
Imaging techniques

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Yang, Jaemoon ; Lee, Jaewon ; Kang, Jinyoung ; Chung, Chan Hwa ; Lee, Kwangyeol ; Suh, Jinsuck ; Yoon, Ho Geun ; Huh, yongmin ; Haam, Seungjoo. / Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications. In: Nanotechnology. 2008 ; Vol. 19, No. 7.
@article{546ce54a48f243b78ea1cf10a2a71e03,
title = "Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications",
abstract = "We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.",
author = "Jaemoon Yang and Jaewon Lee and Jinyoung Kang and Chung, {Chan Hwa} and Kwangyeol Lee and Jinsuck Suh and Yoon, {Ho Geun} and yongmin Huh and Seungjoo Haam",
year = "2008",
month = "2",
day = "14",
doi = "10.1088/0957-4484/19/7/075610",
language = "English",
volume = "19",
journal = "Nanotechnology",
issn = "0957-4484",
publisher = "IOP Publishing Ltd.",
number = "7",

}

Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications. / Yang, Jaemoon; Lee, Jaewon; Kang, Jinyoung; Chung, Chan Hwa; Lee, Kwangyeol; Suh, Jinsuck; Yoon, Ho Geun; Huh, yongmin; Haam, Seungjoo.

In: Nanotechnology, Vol. 19, No. 7, 075610, 14.02.2008.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

AU - Yang, Jaemoon

AU - Lee, Jaewon

AU - Kang, Jinyoung

AU - Chung, Chan Hwa

AU - Lee, Kwangyeol

AU - Suh, Jinsuck

AU - Yoon, Ho Geun

AU - Huh, yongmin

AU - Haam, Seungjoo

PY - 2008/2/14

Y1 - 2008/2/14

N2 - We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

AB - We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

UR - http://www.scopus.com/inward/record.url?scp=38949188601&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38949188601&partnerID=8YFLogxK

U2 - 10.1088/0957-4484/19/7/075610

DO - 10.1088/0957-4484/19/7/075610

M3 - Article

VL - 19

JO - Nanotechnology

JF - Nanotechnology

SN - 0957-4484

IS - 7

M1 - 075610

ER -