Magnetophoretic immunoassay for allergen-specific immunoglobulin E (IgE) in patient samples

Young Ki Hahn, Zongwen Jin, Joo H. Kang, Eunkeu Oh, Hak Sung Kim, Jung Tak Jang, Jinwoo Cheon, Hae Sim Park, Je Kyun Park

Research output: Contribution to conferencePaperpeer-review

Abstract

This paper reports a novel magnetophoretic immunoassay using a microbead conjugated with superparamagnetic nanoparticles under the enhanced magnetic field gradient. A ferromagnetic microstructure connected with a permanent magnet is used to increase the magnetic field gradient (∼104 T m -1) and successfully applied to detect allergen-specific IgEs samples obtained from 44 patients' serum in a hospital. The detectable ranges of human IgEs are 10.68 ng mL-1 to 151 pg mL-1 (Dermatophagoides pteronyssinus) and 19.47 ng mL-1 to 104 pg mL-1 (Dermatophagoides farinae).

Original languageEnglish
Pages320-322
Number of pages3
Publication statusPublished - 2006
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: 2006 Nov 52006 Nov 9

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
CountryJapan
CityTokyo
Period06/11/506/11/9

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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