Malignant Lesions Initially Categorized as Probably Benign Breast Lesions: Retrospective Review of Ultrasonographic, Clinical and Pathologic Characteristics

Hee Jung Moon, Min Jung Kim, Jin Young Kwak, Jung Hyun Yoon, Soo Jin Kim, Yu Mee Sohn, Eun Kyung Kim

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The primary objective of this study was to review the ultrasonographic features of BI-RADS category 3 (" probably benign" ) lesions that eventually proved to be malignant. A second objective was to investigate their clinical and pathologic features according to their palpability and time of biopsy. Thirty-two (0.8%) of 4000 women with lesions that were initially classified as " probably benign" proved to be malignant and formed the study group. The most common reason for a false negative assessment on ultrasound was a failure to recognize suspicious margin characteristics (28 of 32 malignancies, 87.5%). Malignancy was more frequent in palpable (2.4%, 21 of 859) than nonpalpable lesions (0.4%, 11 of 3141, p < 0.001). There was no statistical difference in the mean age, mean size of lesions, or tumor stage between patients who underwent early biopsy (n = 19) or biopsy after 6 months (n = 13). Twenty-nine of the lesions (90.6%) were retrospectively recategorized as BI-RADS 4, which calls for early biopsy. BI-RADS 3 lesions require especially careful assessment.

Original languageEnglish
Pages (from-to)551-559
Number of pages9
JournalUltrasound in Medicine and Biology
Volume36
Issue number4
DOIs
Publication statusPublished - 2010 Apr 1

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breast
lesions
Breast
Biopsy
Neoplasms
margins
tumors

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

Cite this

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Malignant Lesions Initially Categorized as Probably Benign Breast Lesions : Retrospective Review of Ultrasonographic, Clinical and Pathologic Characteristics. / Moon, Hee Jung; Kim, Min Jung; Kwak, Jin Young; Yoon, Jung Hyun; Kim, Soo Jin; Sohn, Yu Mee; Kim, Eun Kyung.

In: Ultrasound in Medicine and Biology, Vol. 36, No. 4, 01.04.2010, p. 551-559.

Research output: Contribution to journalArticle

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